A review on multi-component green synthesis of N-containing heterocycles using mixed oxides as heterogeneous catalysts

Yahya

et al. 2019

IJMS

143

One of the most chronic constraints to crop production is the grain yield reduction near the crop harvest stage by lodging worldwide. This is more prevalent in cereal crops, particularly in wheat and rice. Major factors associated with lodging involve morphological and anatomical traits along with the chemical composition of the stem. These traits have built up the remarkable relationship in wheat and rice genotypes either prone to lodging or displaying lodging resistance. In this review, we have made a comparison of our conceptual perceptions with foregoing published reports and proposed the fundamental controlling techniques that could be practiced to control the devastating effects of lodging stress. The management of lodging stress is, however, reliant on chemical, agronomical, and genetic factors that are reducing the risk of lodging threat in wheat and rice. But, still, there are many questions remain to be answered to elucidate the complex lodging phenomenon, so agronomists, breeders, physiologists, and molecular biologists require further investigation to address this challenging problem.

Section: Chemical Managementmentioning

confidence: 99%

Improving Lodging Resistance: Using Wheat and Rice as Classical Examples

Yahya

et al. 2019

IJMS

143

“…This method has a lot of advantages which are atomic economy, high yield, short time, magnetic recyclable catalyst, one-pot construction of four chemical bonds (one C-C, two C-N and one C=C) to synthesize multiple functionalized 1,5-benzodiazepine compounds. [28,29] The structures of the compound has multiple functional groups on the seven-membered ring, which will have important applications in medicinal and organic chemistry.…”

Section: Introductionmentioning

confidence: 99%

Fe₃O₄@SiO₂‐CeCl₃ Catalyzed Chemoselective Synthesis of Functionalized 3‐Substituted‐1,5‐Benzodiazepines via One‐pot Multicomponent and Domino Reactions

Zhou

Wang²,

Wang³

et al. 2020

Applied Organom Chemis

Fe 3 O 4 @SiO 2-CeCl 3 catalyzed chemoselective synthesis of functionalized 3-substituted-1,5-benzodiazepines via one-pot multicomponent and domino reactions has been developed. During the one-pot synthesis process, one new cycle and four new bonds (one CC , two C-N and one C=C) were constructed by the nucleophilic addition and eliminate reaction (dehydration etc.) process, intramolecular proton transfer and cyclization process. The major advantages of the present method are good to excellent yields, shorter reaction time, simple experimental procedure, easy work up, mild reaction conditions, recyclability of the catalyst and ability to tolerate a variety of functional groups which gives economical as well as ecological rewards. K E Y W O R D S 3-substituted-1,5-benzodiazepines, catalysis, domino reaction, Fe 3 O 4 @SiO 2-CeCl 3 , one-pot multicomponent

“…Moreover, the main advantage of nitrogen-containing heterocyclic moieties is their ability to form salts with better solubility. [9] Pyrazole-attached tetrazoles have received considerable attention in modern heterocyclic chemistry, owing to their broad spectrum of biological activities, plus their medicinal and pharmaceutical applications. [10,11] The large number of triazolidine ring derivatives represents the key building block in diverse therapeutically growing drug candidates.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of novel pyrazole‐based triazolidin‐3‐one derivatives by using ZnO/ZrO₂ as a reusable catalyst under green conditions

Kerru

Bhaskaruni

Gummidi

et al. 2019

Applied Organom Chemis

Self Cite

An efficient approach for the synthesis of 10 novel pyrazole‐based 1,2,4‐triazolidin‐3‐one derivatives catalyzed by ZnO‐loaded ZrO2 as heterogeneous catalyst with ethanol as solvent is described. The structure of the mixed metal oxide catalyst was characterized by various instrumental techniques (scanning electron microscopy, transmission electron microscopy, X‐ray diffraction and Brunauer–Emmett–Teller). In smooth reactions, products were accomplished in excellent yields (90–94%) with short reaction times (≈ 45 min). ZnO/ZrO2 catalyst exhibited good recyclability. The catalyst is reused six times without any noticeable loss of activity. The major advantages of this method are operational simplicity, mild conditions, simple work‐up procedure and broad functional group tolerance.