A review on potential therapeutic properties of Pomegranate (Punica granatum L.)

Abstract

Pomegranate (Punica granatum L. formerly in Punicaceae family) considered to be super food worldwide, belongs to the family Lythraceae. It is primarily cultivated in the Middle East, north and tropical Africa, the Indian subcontinent, Asia and Latin America. The medicinal potential of pomegranate is extensively mentioned in the ancient literature and also used in different system of medicines for a variety of ailments. The chemical constituents of pomegranate have increased the research concern of this fruit in the current years. It includes a variety of bioactive compounds such as quercetin, ellagic acid, punicalagin, pedunculagin, tannic acid, anthocyanins, rutin, catechin and polyphenols. These components of pomegranate possess antioxidant, neuroprotective, anti-inflammatory, anti-angiogenic, anticancerous, anti-mutagenic, cytoprotective, cardiovascular protective, anti-diabetic, anti-ulcerogenic, hepatoprotective, antibacterial and antifungal potentials. It can enhance the male fertility and also protect from the UV induced skin damage. Furthermore, it also illustrate the inhibitory effects on vital metabolic enzymes, stimulate cell differentiation and toxicological properties. The pomegranate also impedes with numerous signalling pathways, which include Bax, Bcl-X, Bad, ERK1/2, JNK, PI3K/AKT, mTOR, PI3K, MAPK and P38. The present review will extensively discuss the above properties of pomegranate and its extracts, supporting the rich nutritive and healthy advantages of the fruit belonging to the monogeneric family.

A Review of the Potential Benefits of Plants Producing Berries in Skin Disorders

“…The most studied plant, pomegranate ( Punica granatum L.), is widely distributed in northern India and in the Mediterranean region. The various biological activities are attributed to the fruits (and their seeds), due to the presence of a variety of phytochemicals including hydrolysable (ellagitannins) and condensed tannins, ellagic acid, punicic acid, and flavonoids (mostly anthocyanins) [ 37 ].…”

Barium Chloride impairs physiology and brain glutamate in Cirrhinus mrigala during a short period of interaction

“…Enzymes; like superoxide dismutase (SOD) and catalase (CAT), play chief role in scavenging free radical produced during stress to the metabolic and physiological processes. Superoxide dismutase has been shown to be the immediate response to oxidative stress in biological system (Puneeth & Chandra, 2020). This is because of the O 2 generation and its conversion to H 2 O 2, which leads to oxidation of cysteine in the antioxidant enzyme, thus confirming BaCl 2 toxicity.…”

Punica granatum L. (Dadim) Punica granatum L. (Dadim), Therapeutic Importance of World’s Most Ancient Fruit Plant

“…It is popular around the world as super food with super therapeutic properties. Previously the genus Punica was placed under monogenic Punicaceae family but after several analyses on molecular and morphological levels revealed that it has close relationship with the family named as Lythraceae 20,21 . This family consists of one genus and two species only 22 .…”