Infertility is a burning problem all over the globe. Many couples yearn to have babies in their life. Infertility is very common issue faced by many couples from years. They use conventional type of therapy for many years and then approach Ayurveda. Vandhyatva is term used in Ayurveda for sterility. This sterility comes due to many factors occurring inside and outside of the body. Rutu, Kshetra, Ambu and Beej are the Garbhautpadkar bhava (factors important for fertilization and implantation) which are immensely important for normal fertilization and attachment of the foetus in the womb. Disorder in any of the above factor can cause infertility. Kshetra means the site where the foetus will reside. It should be normal and healthy for its survival. Derangement or pathology in it may cause failure to conceive. There are various problems which causes pathology in uterus such as endometriosis, adenomyosis, fibrosis and atrophy are a few of them. In this case report, we have a 32 years old female patient with small uterus and an irregular menstruation. The cause for her infertility was long term use of hormonal therapy for contraception purpose. She was advised to do Panchkarma for eight days and herbomineral formulations were prescribed to her for five months. After 3 months, she got her regular menses. USG pelvis before and after treatment were advised to her and positive results were obtained with Ayurvedic treatment.