Diabetes mellitus refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. Due to the burden of type 2 diabetes and its complications, much attention has been given to prevention, beginning with identifying at-risk individuals prior to diagnosis. Prediabetes is one of the major clinically entity, striking resemblance with that of Prameha in Ayurveda and Diabetes Mellitus having close resemblance with Madhumeha as described in Ayurveda. Prameha is of 20 types based on the type of urination and on the basis of Dosha predominance it is categorized namely as Kaphaja, Pittaja and Vataja Prameha. Prameha Nidana are of 2 types -Sahaja (hereditary) and Apathya Nimitaja (acquired). Apathya Nimitaja (Acquired) is further of three types-Kaphakara, Pittakara and Vatakara. Etiological factors of Prameha can also be categorized into Samanya Nidana (General factors) and Vishesha Nidana (Specific factors). If different clinical stages of Prameha (Prediabetes) are not managed in due time it may lead to Madhumeha(diabetes). Nidana Parivarjana plays a first step in the fight against any disease. The study of Nidana (etiological factors) reveals the rich knowledge of the Ayurveda in the prevention of Diabetes by following Nidana Parivarjana.

Basti Karma is the most widely used and highly effective treatment modality in Panchakarma. Though Basti is specially indicated for Vatika diseases but it is mentioned in vitiation of all the Vata, Pitta, Kapha, Rakta Doshika disorders. Correctly given Basti will stay in the Pakawashaya, Shroni, Nabhi and Adhobhaga. Basti Dravya will reach the entire Srotasa, in view of its Veerya and produces alleviating   action  Shamanadi  karmas. References regarding  Basti Karmuktwa  were collected from various classical and Ayurveda published works, published research papers from Pub Med, Google Scholar and compilation was done. Concept of Pharmacodynamics of Basti  was studied in detail.  Basti is most often recommended practice in Vata Roga Chikitsa.  Most of the previous studies have emphasized on the importance of Basti  in Vata vyadhis; however there were limited studies carried out on pharmacodynamics  of Basti only. Pharmacodynamics outcome of Basti Karma may be due to functioning of the one or more effect of different mechanism.  

Introduction: Hypertension, one of the grave conditions, accounts for 6% of deaths worldwide. In 2010 increased blood pressure was the cause of an estimated 9.4 million deaths. According to Ayurveda, systemic arterial hypertension can be considered as Tridoshaja condition with predominance of Vata and Pitta along with invovment of Rasa, Rakta and Meda . Basti Karma a medicated enema procedure is the best treatment for vitiated Vata Dosha and it regulates the movement of Vata Dosha Objectives: The present study was conducted to evaluate effect of Triphaladi Kala Basti procedure given along with Arjuna Punarnavadi Ghanavati in the management of essential hypertension. Materials and Methods: Fifteen patients who were diagnosed cases of essential hypertension as per the 7 th JNC and World Health Organization criteria for diagnosis of hypertension were treated with Triphaladi Basti followed by oral administration of Arjuna Punarnavadi Ghanavati . Results: Administration of Basti and Arjuna Punarnavadi Ghanavati were effective in reducing both systolic and diastolic blood pressure level which was highly significant ( P < 0.001). Conclusion: Triphaladi Kala Basti procedure along with oral administration of Arjuna Punarnavadi Ghanavati is moderatly effective in management of systemic arterial hypertension.

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Introduction: Panchakarma is considered as one of the specialities of Kayachikitsa which includes five major therapeutic procedures of detoxification and body purification, along with many other supportive procedures. In fact, Panchakarma can be used efficiently in all the branches of Astang-Ayurved and it can also be beneficial in Kaumarbhritya for a comprehensive cure for many child disorders. This review was carried out to study the concept of Panchakarma in children and explore the variations and significance of Panchakarma in Bala-Roga. Materials & Methods: References regarding Panchakarma in Children were collected from various classical Ayurveda textbooks, published research papers from Internet sources, previous work done and compilation was done. Concept of Panchakarma in Children was studied in detail. Results: Most of the previous studies have emphasized on the importance of Panchakarma in children; however there were limited clinical studies have been carried out on procedural effectiveness of Panchkarma in children. Panchakarma measures executed with precautions is equqlly effective in a child as it results in adult. Conclusion: The knowledge and experience of Panchakarma in pediatric conditions is the key to successful administration of Panchakarma in children. Increasing and mainstreaming Panchakarma procedures among children in Ayurveda hospitals will definitely provide a new hope in management of child disorders.