Introduction: Hypertension, one of the grave conditions, accounts for 6% of deaths worldwide. In 2010 increased blood pressure was the cause of an estimated 9.4 million deaths. According to Ayurveda, systemic arterial hypertension can be considered as Tridoshaja condition with predominance of Vata and Pitta along with invovment of Rasa, Rakta and Meda . Basti Karma a medicated enema procedure is the best treatment for vitiated Vata Dosha and it regulates the movement of Vata Dosha Objectives: The present study was conducted to evaluate effect of Triphaladi Kala Basti procedure given along with Arjuna Punarnavadi Ghanavati in the management of essential hypertension. Materials and Methods: Fifteen patients who were diagnosed cases of essential hypertension as per the 7 th JNC and World Health Organization criteria for diagnosis of hypertension were treated with Triphaladi Basti followed by oral administration of Arjuna Punarnavadi Ghanavati . Results: Administration of Basti and Arjuna Punarnavadi Ghanavati were effective in reducing both systolic and diastolic blood pressure level which was highly significant ( P < 0.001). Conclusion: Triphaladi Kala Basti procedure along with oral administration of Arjuna Punarnavadi Ghanavati is moderatly effective in management of systemic arterial hypertension.

ObjectiveThe world continues to face the COVID-19 crisis, and efforts are underway to integrate traditional medicine interventions for its effective management. The study aimed to determine the efficacy of the “AYURAKSHA” kit in terms of post-interventional percentage of COVID-19 IgG positivity, immunity levels, and quality of life (QoL) against COVID-19.MethodThis was a non-randomized controlled, prospective intervention trial, done after the distribution of 80,000 AYURAKSHA kits (constituent of Sanshamani Vati, AYUSH Kadha, and Anu Taila) among Delhi police participants in India. Among 47,827 participants, the trial group (n = 101) was evaluated with the positivity percentage of IgG COVID-19 and Immune Status Questionnaire (ISQ) scores as a primary outcome and the WHO Quality of Life Brief Version (QOL BREF) scores along with hematological parameters as a secondary outcome in comparison to the control group (n = 71).ResultsThe data showed that the percentage of COVID-19 IgG positivity was significantly lower in the trial group (17.5 %) as compared to the control group (39.4 %, p = 0.003), indicating the lower risk (55.6%) of COVID-19 infection in the trial group. The decreased incidence (5.05%) and reduced mortality percentage (0.44%) of COVID-19 among Delhi police officers during peak times of the pandemic also corroborate our findings. The ISQ score and WHO-QOL BREF tool analysis showed the improved scores in the trial group when compared with the controls. Furthermore, no dysregulated blood profile and no increase in inflammation markers like C-reactive protein, erythrocyte sedimentation rate, Interleukin-6 (IL-6) were observed in the trial group. However, significantly enhanced (p = 0.027) IL-6 levels and random blood sugar levels were found in the control group (p = 0.032), compared to a trial group (p = 0.165) post-intervention. Importantly, the control group showed more significant (p = 0.0001) decline in lymphocyte subsets CD3+ (% change = 21.04), CD4+ (% change = 20.34) and CD8+ (% change = 21.54) levels than in trial group, confirming more severity of COVID-19 infection in the control group.ConclusionThe AYURAKSHA kit is associated with reduced COVID-19 positivity and with a better quality of life among the trial group. Hence, the study encourages in-depth research and future integration of traditional medicines for the prevention of the COVID-19 pandemic.Clinical trial registrationhttp://ctri.nic.in/, identifier: CTRI/2020/05/025171.

Ayurvedaas a holistic science lays great emphasis on lifestyle modification under Ahar(Diet), Vihar(Daily regimen) and Aoushadh(triad for prevention and treatment of all diseases).Among vihara nidrais considered as a very influencing factorin Ayurvedaclassics. Nindrais considered as one of the sub pillar of Trayopasthambh which includes Ahaar, Bhramcharya, and Nidra. Ahaar nourishes our body, Brahmcharya nourishes mind but Nidra nourishes both bodyand mind. Sleep maintains the functions of entire body through homeostasis; contemporary science states that NREM (non rapid eye movement) sleep may be state of brain repair i.e. of increased cerebral protein synthesis or of reprogramming the brain so that the information achieved in a wakeful functioning is most efficiently assimilated. Ayurvedasubstantiates the similar opinion by designating it as ‘Bhut-Dhatri‘which nourishes the all living beings.

Ojas is considered as essence of seven Dhatus or equivalent to Bala or Sleshma. Ojas can also be considered as living radiant energy present in human body. In Ayurveda literature the term Oja is not clearly explained by Ayurveda community. The classical Ayurveda text describes Ojakshaya as one of the Ojavikara which may be prevalent in various diseases. The pathogenesis of Madhumeha (Diabetes Mellitus) also describes this phenomenon. The prevalence of Oja kshaya can be clinically evaluated in the patients of Madhumeha and the same if kept in mind during treatment may arrest the further progress of the disease to complications like Diabetic Retinopathy, Neuropathy etc. In Ayurveda classics Ojakshaya is described in relation of Madhumeha. So, there will be prevalence of Ojakshaya in patient of Madhumeha (Diabetes Mellitus). Therefore, in this review article an attempt is made to understand the concept of Oja and Ojakshaya in diabetes mellitus.

Amavata is a most commonest disorder seen in middle age people which affects both the sex, characterized by Angamarda (body Pain), Aruchi (loss of taste), Thrishna (thirst), Alasya (lack of enthusiasm), Gourava (heaviness), Klama (tiredness without doing work), Apaka (indigestion) and fever. In the later stage pain may begin to migrate from place to place with a Vrishchika damshavat Vedana (intense stinging type of pain) and burning sensation. Similar clinical symptoms seen in the disease Rheumatoid Arthritis in modern science. The Treatment principle includes the pain management and steroids in the Allopathic medicine. In Ayurveda according to our classics Langhana (light diet or fasting), Deepana Pachana (Appetizers, Digestives and Carminatives), Samshodhana (Different Purifications) are suggested. The aim of this study was to evaluate the efficacy of Valukasveda and Vaitarana Basti in the management of Amavata. In the present clinical trial 30 patients suffering with Amavata were selected and divided into two groups with 15 patients each administered with Valukasveda and Vaitarana Basti. Statistical analysis showed better result in relieving the sign and symptoms of Amavata (Rheumatoid arthritis) in both the groups. By comparision Group B (Valuka sveda and Vaitarana Basti) showed better result than Valuka sveda alone (Group A)