A review on versatile applications of transition metal complexes incorporating Schiff bases

Abstract

Antimicrobial Dyes Polymers a b s t r a c t Schiff bases and their complexes are versatile compounds synthesized from the condensation of an amino compound with carbonyl compounds and widely used for industrial purposes and also exhibit a broad range of biological activities including antifungal, antibacterial, antimalarial, antiproliferative, anti-inflammatory, antiviral, and antipyretic properties. Many Schiff base complexes show excellent catalytic activity in various reactions and in the presence of moisture. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The high thermal and moisture stabilities of many Schiff base complexes were useful attributes for their application as catalysts in reactions involving at high temperatures. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behaviour. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. This review compiles examples of the most promising applied Schiff bases and their complexes in different areas.

Synthesis of Co(II) and Cr(III) salicylidenic Schiff base complexes derived from thiourea as precursors for nano-sized Co3O4 and Cr2O3 and their catalytic, antibacterial properties

“…Schiff base ligands are easily synthesized and form complexes with almost all metal ions. Over the past few years, there have been many reports on their applications in biology including antibacterial [1], antifungal [2], anticancer [3], antioxidant, antiinflammatory [4], antimalarial [5], antiviral activity [6] and also as catalyst in several reactions such as polymerization reaction, reduction of thionyl chloride, oxidation of organic compounds, reduction reaction of ketones, aldol reaction, Henry reaction, epoxidation of alkenes, hydrosilylation of ketones, Diels-Alder reaction [7,8]. The central metal ions in these complexes act as active sites for catalyzing chemical reactions such as oxidation of toluene.…”

Synthesis, Characterization and Antimicrobial Activity of some Metal Complexes Derived from Thiazole Schiff Bases with In-vitro Cytotoxicity and DNA Cleavage Studies

“…1 Schiff bases are considered as privileged ligands because they are easily prepared by condensation of aldehydes or ketones with amines and are able to stabilize different metals in various oxidation states. 2,3 The importance of Schiff base complexes for bioinorganic chemistry, biomedical applications, supramolecular chemistry, catalysis and material science, separation and encapsulation processes, and formation of compounds with unusual properties and structures has been well recognized and reviewed.…”

Investigation of the Electronic and pH-Sensing properties of Hydroxyl-Functionalized Imine-Linked Polymers via the UV-vis Absorption Spectra and the Density Functional Theory (DFT) Calculations

“…The multifunctional properties of ILPs are related to their selective structural design which, exhibit an extended conjugated backbone accessible for functionalization and free nitrogen sites available for protonation and metal ion-coordination [3,8,9].…”