A rhodol-hemicyanine based ratiometric fluorescent probe for real-time monitoring of glutathione dynamics in living cells

Abstract

A new rhodol-hemicyanine based ratiometric and reversible fluorescent probe has been developed for real-time monitoring of glutathione dynamics in living cells.

A Turn‐On Sensor for Highly Sensitive and Selective Detect Heparin in Human Serum Albumin

“…This type of dye is endowed with excellent chemical and photophysical properties due to the efficient ICT process. [27][28][29] 1,8-naphthalimide, as a classical fluorophore, has been developed and applied in different fields as a role of a molecular fluorescence sensor based on its small molecular structure and the excellent properties of rigid plane frame, easy modification and stability. The new compounds can be easily synthesized by Suzuki Miyaura coupling reaction.…”

“…Hemicyanine dyes usually contain a conjugated benzothiolium or indolium group as an electron acceptor and a hydroxyl or amino group as an electron donor to form a donor‐ð‐acceptor (D‐ð‐A) system. This type of dye is endowed with excellent chemical and photophysical properties due to the efficient ICT process [27–29] . 1,8‐naphthalimide, as a classical fluorophore, has been developed and applied in different fields as a role of a molecular fluorescence sensor based on its small molecular structure and the excellent properties of rigid plane frame, easy modification and stability.…”

Reversible Reaction‐Based Fluorescent Probes for Dynamic Sensing and Bioimaging

“…Recently, Guo's group reported the reversible fluorescent probe 10 for the real-time monitoring of GSH dynamics (Scheme 3). [19] This rhodol-hemicyanine hybrid shows greatly red-shifted emission at 688 nm. Probe 10 undergoes a reversible Michael reaction with GSH at the activated double bond to form adduct product 10′ which has blue-shifted emission at 560 nm.…”

A novel AIE fluorescent probe for the monitoring of aluminum ions in living cells and zebrafish

“…Reversibility and regeneration are also essential factors for the development of devices for sensing analytes in practical applications. [41][42][43][44][45][46][47][48][49][50][51][52][53] We first evaluated the fluorescence response of the in situ product BTD-Al 3+ toward other analytes, such as Cys, Hcy, GSH, S 2− , SO 3…”