A scanning electron microscopic study on thrombogenicity of intraarterial catheters for chemotherapeutic treatment in head and neck cancer

Abstract

Standard anticoagulation was ineffective in clot prevention. Heparinized catheters might potentially reduce the risk of clot formation. A delivery system should be engaged for continuous irrigation of catheters with heparinized saline.

Thrombogenicity and Blood Coagulation of a Microcatheter Prepared from Carbon Nanotube−Nylon-Based Composite

“…Introduction. Since thrombus formation on the surface of a catheter is an inevitable phenomenon, there has been a wide range of studies on thrombogenicity. − It is generally accepted that the thrombus growth mechanism is very complex and that all of the blood components take part in the formation of thrombi on the surfaces of the biomaterials. , To solve this problem, some researchers have been trying to understand the formation mechanism while others have developed better performing catheters utilizing new materials. In the present paper, we report on the phenomenological results of an evaluation of the in vivo thrombogenicity, and the in vitro blood coagulation properties of a novel microcatheter fabricated using multiwalled carbon nanotubes as a filler for nylon.…”