According to the application requirements of state prediction and health management (PHM) technology in the field of UAV, this paper analyzes the functional requirements of UAV PHM system by referring to the research results and application experience of PHM technology at home and abroad and combining with the current situation of UAV support in China. Furthermore, this paper designs the architecture of UAV PHM system and introduces the workflow of the system in detail, which provides guidance and reference for the improvement of UAV comprehensive support level.