A sensitive glucose biosensor based on the abundant immobilization of glucose oxidase on hollow Pt nanospheres assembled on graphene oxide–Prussian Blue–PTC-NH2 nanocomposite film

Xu, Wailan; He, Junlin; Gao, Liuliu; Zhang, Jing; Hui, Junmin; Guo, Yanlei; Li, Wenjuan

doi:10.1016/j.jelechem.2015.01.004

Cited by 18 publications

(4 citation statements)

References 43 publications

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“…Furthermore, the application of different nanomaterials such as graphene, carbon nanotubes, quantum dots, magnetic particles, and gold nanoparticles deposited on PB/PBA offer new avenues to increase the sensitivity [19,20]. In previous studies, PB/PBA-based biosensors were considered to be one of the most efficient electron-transfer mediators for applications including the determination of tumor markers, antihypertensive drugs, glucose, lactate, ascorbic acid, DNA, ions, and pH [21][22][23][24][25][26][27][28]. Thus, several strategies for signal amplification have been used to enhance the electrochemical response.…”

Section: Introductionmentioning

confidence: 99%

The Application of Prussian Blue Nanoparticles in Tumor Diagnosis and Treatment

Gao

Wang

Cheng

et al. 2020

Sensors

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Prussian blue nanoparticles (PBNPs) have attracted increasing research interest in immunosensors, bioimaging, drug delivery, and application as therapeutic agents due to their large internal pore volume, tunable size, easy synthesis and surface modification, good thermal stability, and favorable biocompatibility. This review first outlines the effect of tumor markers using PBNPs-based immunosensors which have a sandwich-type architecture and competitive-type structure. Metal ion doped PBNPs which were used as T1-weight magnetic resonance and photoacoustic imaging agents to improve image quality and surface modified PBNPs which were used as drug carriers to decrease side effects via passive or active targeting to tumor sites are also summarized. Moreover, the PBNPs with high photothermal efficiency and excellent catalase-like activity were promising for photothermal therapy and O2 self-supplied photodynamic therapy of tumors. Hence, PBNPs-based multimodal imaging-guided combinational tumor therapies (such as chemo, photothermal, and photodynamic therapies) were finally reviewed. This review aims to inspire broad interest in the rational design and application of PBNPs for detecting and treating tumors in clinical research.

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Section: Introductionmentioning

confidence: 99%

The Application of Prussian Blue Nanoparticles in Tumor Diagnosis and Treatment

Gao

Wang

Cheng

et al. 2020

Sensors

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“…Nanostructures have been widely utilized for biosensing applications due to their large surface area, great mass transfer ability, excellent chemical stability, suitable microenvironment for the immobilization of enzyme and high bioactivities. [1][2][3][4] Owing to the advantages of operation simplicity, lower cost and higher selectivity and suitable for real time detection, amperometric biosensors become a kind of the most applied biomonitors. [5][6][7][8] Nanomaterials with enhanced electron transduction capability and high electrocatalytic performance, such as the noble metal nanomaterials, carbon nanotubes, graphene, etc., are mostly used to fabricate amperometric biosensors.…”

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confidence: 99%

Glucose Biosensor Based on Mesoporous Pt Nanotubes

Yang¹,

Shi²,

Yang³

et al. 2017

J. Electrochem. Soc.

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One-dimensional (1D) mesoporous Pt nanotubes (MPtNTs, internal diameter is about 50 nm) with different wall thicknesses (from 7.2 nm to 12.8 nm) were synthesized and used as carriers of glucose oxidase to fabricate amperometric glucose biosensors. The MPtNTs modified electrodes had good response toward H 2 O 2 . The response current of the MPtNTs based biosensor toward glucose increased with the decrease of the wall thickness. The as-prepared MPtNTs biosensors with a wall thickness of 7.2 nm manifested high sensitivity (3.19 μA mM −1 ). Due to its unique structure and morphology, the MPtNTs based biosensor can achieve relative low detection limit. The limit of detection (LOD) of the MPtNTs based biosensor is calculated to be 0.2 μM, and the linear range is from 0.025 to 2.20 mM. The value of Michaelis constant (K m ) is evaluated to be as low as 3.4 mM.

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“…It was shown that the presence of pyrrole increased the electronic interaction between NPs and the polypyrrole matrices [ 173 ]. To improve the sensitivity and prevent GOD from leaching away, a sensitive glucose sensor based on the immobilization of GOD on hollow Pt nanospheres assembled on graphene oxide (GO)-Prussian Blue (PB)-3,4,9,10-perylenetetracarboxylic dianhydride derivative (PTC-NH 2 ) nanocomposite film has been reported [ 174 ]. Interestingly, to pursue high performance for non-enzymatic glucose sensors, the modified electrode coupling with concentrated hydroxide electrolyte based on a fast conversion of the redox couple (Ni(OH) 2 ↔NiOOH: Ni II /Ni III ) on Ni(OH) 2 nanoparticles-modified carbon (Ni(OH) 2 /C) nanocomposites has been established.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Biomedical Probes Based on Inorganic Nanoparticles for Electrochemical and Optical Spectroscopy Applications

Yakoh

Pinyorospathum

Siangproh

et al. 2015

Sensors

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Inorganic nanoparticles usually provide novel and unique physical properties as their size approaches nanometer scale dimensions. The unique physical and optical properties of nanoparticles may lead to applications in a variety of areas, including biomedical detection. Therefore, current research is now increasingly focused on the use of the high surface-to-volume ratios of nanoparticles to fabricate superb chemical- or biosensors for various detection applications. This article highlights various kinds of inorganic nanoparticles, including metal nanoparticles, magnetic nanoparticles, nanocomposites, and semiconductor nanoparticles that can be perceived as useful materials for biomedical probes and points to the outstanding results arising from their use in such probes. The progress in the use of inorganic nanoparticle-based electrochemical, colorimetric and spectrophotometric detection in recent applications, especially bioanalysis, and the main functions of inorganic nanoparticles in detection are reviewed. The article begins with a conceptual discussion of nanoparticles according to types, followed by numerous applications to analytes including biomolecules, disease markers, and pharmaceutical substances. Most of the references cited herein, dating from 2010 to 2015, generally mention one or more of the following characteristics: a low detection limit, good signal amplification and simultaneous detection capabilities.

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A sensitive glucose biosensor based on the abundant immobilization of glucose oxidase on hollow Pt nanospheres assembled on graphene oxide–Prussian Blue–PTC-NH2 nanocomposite film

Cited by 18 publications

References 43 publications

The Application of Prussian Blue Nanoparticles in Tumor Diagnosis and Treatment

The Application of Prussian Blue Nanoparticles in Tumor Diagnosis and Treatment

Glucose Biosensor Based on Mesoporous Pt Nanotubes

Biomedical Probes Based on Inorganic Nanoparticles for Electrochemical and Optical Spectroscopy Applications

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