A human face contains a wealth of information about an individual, with which an observer can instinctively make a judgment on the attractiveness of the face. However, despite the profuse literature on facial and smile attractiveness, their origins, determinants, and perceptions remain controversial. The axiom in face processing research is that a face is perceived as an amalgamation of its features, and is referred to as “whole” or “holistic” perception. It is pertinent to the clinician involved in the provision of esthetic restorations to understand this holistic process of face recognition and perception of smile attractiveness. This review paper addresses face recognition and perception of attractiveness by reviewing the holistic perception of faces, including the multidimensional face‐space model, and also reviews the smile and facial attractiveness according to the average, multiple motive, and secondary sex characteristics theories.