A Short-Term Double-Blind Trial of Aerosol Triamcinolone Acetonide in Steroid-Dependent Patients with Severe Asthma

Kriz, Robert J.; Chmelik, Frank; doPico, Guillermo A.; Reed, Charles E.

doi:10.1378/chest.69.4.455

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From Early Promise To the Time Of Certitude1

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1977

2012

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Cited by 22 publications

(1 citation statement)

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“…Early studies in the 1970s used inhaled beclomethasone dipropionate and triamcinolone acetate in moderate to severe asthma and showed that these drugs were effective in improving lung function and reducing symptoms despite tapering oral corticosteroids. [4][5][6] The introduction of ICS dramatically and effectively changed the conventional approach to asthma therapy. The institution of ICS made it possible to replace, in most of the patients, the chronic use of oral corticosteroids, thereby avoiding side effects that were often severe and debilitating.…”

Section: From Early Promise To the Time Of Certitudementioning

confidence: 99%

Corticosteroids

Louis

Schleich

Barnes

2012

Clinics in Chest Medicine

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Section: From Early Promise To the Time Of Certitudementioning

confidence: 99%

Corticosteroids

Louis

Schleich

Barnes

2012

Clinics in Chest Medicine

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Clinical aerosols II. Therapeutic aerosols

Lourenço¹

1982

Archives of Internal Medicine

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The current uses of clinical aerosols such as water, saline, mucolytics, bronchodilators, cromolyn sodium, corticosteroids, and antimicrobials have been reviewed. The benefits of water, saline, and detergent aerosols continue to be surrounded by uncertainty and controversy. Aerosolized mucolytic and proteolytic agents have not been conclusively shown to be of substantial value in the improvement of respiratory disorders. Favorable bronchodilator therapy is achieved with aerosols of certain sympathomimetic and anticholinergic agents. However, successful therapy depends on the dose administered and the site of aerosol deposition in the lung. The prophylactic use of cromolyn sodium in patients with asthma is another useful application of aerosols. Topically active corticosteroid aerosols are increasingly being used since they may reduce risks of systemic effects from corticosteroids. Research on uncommonly aerosolized agents has widened the spectrum of therapeutic applications of aerosols.

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Clinical Effect of Aerosol Triamcinolone Acetonide in Bronchial Asthma

Grieco¹

1978

Arch Intern Med

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A Short-Term Double-Blind Trial of Aerosol Triamcinolone Acetonide in Steroid-Dependent Patients with Severe Asthma

Cited by 22 publications

References 23 publications

Corticosteroids

Corticosteroids

Clinical aerosols II. Therapeutic aerosols

Clinical Effect of Aerosol Triamcinolone Acetonide in Bronchial Asthma

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