A simple and efficient approach for synthesis of pseudoionone from citral and acetone catalyzed by powder LiOH·H2O

Xing, Kongqiang; You, Kuiyi; Yin, Dulin; Yuan, Zhiye; Mao, Liang

doi:10.1016/j.catcom.2009.10.002

Cited by 14 publications

(13 citation statements)

References 10 publications

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“…Interestingly, LiOH significantly improved the ethanol conversion to 11.2% with 56.1% selectivity to butanol, even much higher than that over the C2H5ONa or NaOH at the same mole of LiOH. In accordance with previous results about the high activity of Li based catalysts in condensation reactions [38][39][40], LiOH herein provided the base sites to promote both aldol condensation and ethanol dehydrogenation reactions, and afforded the elevated butanol yield. Therefore, the binary catalyst of FeNiOx and LiOH was identified as the optimal candidate for the further study in the following sections.…”

supporting

confidence: 91%

Catalytic upgrading of ethanol to butanol over a binary catalytic system of FeNiO and LiOH

Pang

Wang

Liu

et al. 2020

Chinese Journal of Catalysis

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supporting

confidence: 91%

Catalytic upgrading of ethanol to butanol over a binary catalytic system of FeNiO and LiOH

Pang

Wang

Liu

et al. 2020

Chinese Journal of Catalysis

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“…α,β-Unsaturated aldehydes serve as important intermediates in the organic synthesis of an extended range of fine chemicals for use in products such as flavoring agents, fragrances and pharmaceuticals [ 1 – 3 ]. For example, citral (3,7-dimethyl-2,6-octadien-1-al) is in high demand for the production of ionones, vitamins A and E, and carotenoids [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Efficient whole-cell oxidation of α,β-unsaturated alcohols to α,β-unsaturated aldehydes through the cascade biocatalysis of alcohol dehydrogenase, NADPH oxidase and hemoglobin

et al. 2021

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Background α,β-Unsaturated aldehydes are widely used in the organic synthesis of fine chemicals for application in products such as flavoring agents, fragrances and pharmaceuticals. In the selective oxidation of α,β-unsaturated alcohols to the corresponding α,β-unsaturated aldehydes, it remains challenging to overcome poor selectivity, overoxidation and a low atom efficiency in chemical routes. Results An E. coli strain coexpressing the NADP+-specific alcohol dehydrogenase YsADH and the oxygen-dependent NADPH oxidase TkNOX was constructed; these components enabled the NADP+ regeneration and catalyzed the oxidation of 100 mM 3-methyl-2-buten-1-ol to 3-methyl-2-butenal with a yield of 21.3%. The oxygen supply was strengthened by introducing the hemoglobin protein VsHGB into recombinant E. coli cells and replacing the atmosphere of the reactor with pure oxygen, which increased the yield to 51.3%. To further improve catalytic performance, the E. coli cells expressing the multifunctional fusion enzyme YsADH-(GSG)-TkNOX-(GSG)-VsHGB were generated, which completely converted 250 mM 3-methyl-2-buten-1-ol to 3-methyl-2-butenal after 8 h of whole-cell oxidation. The reaction conditions for the cascade biocatalysis were optimized, in which supplementation with 0.2 mM FAD and 0.4 mM NADP+ was essential for maintaining high catalytic activity. Finally, the established whole-cell system could serve as a platform for the synthesis of valuable α,β-unsaturated aldehydes through the selective oxidation of various α,β-unsaturated alcohols. Conclusions The construction of a strain expressing the fusion enzyme YsADH-(GSG)-TkNOX-(GSG)-VsHGB achieved efficient NADP+ regeneration and the selective oxidation of various α,β-unsaturated alcohols to the corresponding α,β-unsaturated aldehydes. Among the available redox enzymes, the fusion enzyme YsADH-(GSG)-TkNOX-(GSG)-VsHGB has become the most recent successful example to improve catalytic performance in comparison with its separate components.

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“…In particular, the products obtained by aldol condensation with natural materials are preferred when they are used to produce flavor, cosmetics, pharmaceuticals, etc. [4][5][6]. This trend is increasingly being researched and invested to produce products that have a natural origin, good for human health.…”

Section: Introductionmentioning

confidence: 99%

Vanillin conversion by aldol condensation using hydrotalcite Mg-Al and modified-Y zeolite as heterogeneous catalysts

Thai¹,

Thư²

2021

Vietnam J. Sci. Technol.

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Mg-Alhydrotalcite, MgO-Al2O3 mixed oxides and modified-Y zeolite (sulfated Y zeolite and copper ion-exchanged Y zeolite) were prepared and characterized by XRD, EDX and XRF techniques. These materials were used as heterogeneous catalysts in aldol condensation of vanillin and acetone.The obtained results showed that the heterogeneous acid catalysts as modified-Y zeolites were more effective than the heterogeneous base catalysts as hydrotalcite Mg-Al and MgO-Al2O3 mixed oxides in aldol condensation reaction of vanillin. The highest conversion of vanillin was 95.5% when the reaction was carried out at 120oC in 5 hours, using sulfated Y zeolite.

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A simple and efficient approach for synthesis of pseudoionone from citral and acetone catalyzed by powder LiOH·H2O

Cited by 14 publications

References 10 publications

Catalytic upgrading of ethanol to butanol over a binary catalytic system of FeNiO and LiOH

Catalytic upgrading of ethanol to butanol over a binary catalytic system of FeNiO and LiOH

Efficient whole-cell oxidation of α,β-unsaturated alcohols to α,β-unsaturated aldehydes through the cascade biocatalysis of alcohol dehydrogenase, NADPH oxidase and hemoglobin

Vanillin conversion by aldol condensation using hydrotalcite Mg-Al and modified-Y zeolite as heterogeneous catalysts

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