A simple and rapid method for direct determination of Al(III) based on the enhanced resonance Rayleigh scattering of hemin-functionalized graphene-Al(III) system

Yu, Ling; Chen, Ling Xiao; Dong, Jiancheng; Li, Nian Bing; Luo, Hong Qun

doi:10.1016/j.saa.2015.11.019

Cited by 11 publications

(2 citation statements)

References 48 publications

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“…[ 37,38 ] These aggregates affect the dynamical and structural properties of the hemin molecules as well as their functions: the local electronic structure at the iron‐center is altered upon dimerization along with the change in the solvent interactions and axial coordination. [ 38 ] For that reason, diverse research teams have reported the immobilization of hemin on high surface area materials such as graphene, [ 10,39–41 ] tungsten disulfide, [ 42 ] and porous coordination polymers through which these materials act as scaffolds akin to the protein structure of the enzyme. The resulting composites produced a high open surface area, which allows the access of the substrates and release of the products while maintaining the catalytic efficiency of the encapsulated monomeric hemin molecules.…”

Section: Introductionmentioning

confidence: 99%

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

2020

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The fabrication of biomimetic catalysts as substituents for enzymes is of critical interest in the field due to the problems associated with the extraction, purification, and storage of enzymes in sensing applications. Of these mimetics, hemin/coordination polymer‐based nanocomposites, mainly hemin/metal–organic frameworks (MOF), have been developed for various biosensing applications because of the unique properties of each component, while trying to mimic the normal biological functions of heme within the protein milieu of enzymes. This critical review first discusses the different catalytic functions of heme in the body in the form of enzyme/protein structures. The properties of hemin dimerization are then elucidated with the supposed models of hemin oxidation. After that, the progress in the fabrication of hemin/MOF nanocomposites for the sensing of diverse biological molecules is discussed. Finally, the challenges in developing this type of composites are examined as well as possible proposals for future directions to enhance the sensing performance in this field further.

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Section: Introductionmentioning

confidence: 99%

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

2020

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“…[14][15][16] With its two-dimensional matrix structure, graphene is considered to be a single layer of stripped graphite 17 and plays multiple roles in biomedical applications through introducing hydroxyl, carbonyl, and epoxy groups, 18,19 as well as in antibodies, medicines, and functional nanoparticles. 16,20,21 For example, graphene can be loaded with hemin through a π-π conjugation effect, 22,23 and the amino groups in streptavidin can be reacted with carboxyl groups on modified graphene. 24,25 A biotinylated MHC monomer, thus, can be loaded onto a graphene surface through biotin-streptavidin effect.…”

Section: Introductionmentioning

confidence: 99%

A novel absorption spectrometric method, based on graphene nanomaterials, for detection of hepatocellular carcinoma-specific T lymphocyte cells

Zhu

et al. 2018

IJN

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IntroductionDetection of antigen-specific cytotoxic T lymphocytes (CTLs) is the foundation for understanding hepatocellular carcinoma immune pathology and hepatocellular carcinoma immunotherapy. However, the classical method for labeling CTLs, major histocompatibility complex (MHC)–peptide tetramer, has drawbacks and needs further improvement.Materials and methodsHere, as a new detection probe, a graphene-based MHC–peptide multimer was developed for sensitively and selectively identifying hepatocellular carcinoma-specific T-cells. To assess its detection efficiency, reduced graphene oxide (RGO) was functionalized with hemin and streptavidin to prepare a functionalized HRGO–streptavidin complex. Biotinylated MHC–peptide monomer was subsequently constructed onto HRGO to generate a detection probe for CTL labeling. The number of T-cells was detected through the reaction between HRGO and tetramethylbenzidine.ResultsUsing HRGO/MHC–peptide multimers, the number of T-cells was efficiently detected in both the induction system in vitro and in peripheral blood of patients.ConclusionHRGO/MHC-peptide multimers methodology has application prospects in the detection of antigen peptide-specific T cells.

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Resonance Rayleigh scattering methods for the determination of chitosan with Congo red as probe

Zhang

Guo

et al. 2017

Luminescence

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Two methods were presented for the sensitive and selective determination of chitosan (CTS) with Congo red (CR) as probe based on resonance Rayleigh scattering (RRS) intensities in health products. In weakly acidic buffer solution, the binding of CTS to CR, could result in the enhancement of the RRS intensities. Moreover, after adding OP emulsifier (octyl-phenyl polyoxyethylene ether) to the system, the RRS intensities showed more significantly enhancement. The maximum RRS signals for the CTS-CR system and the CTS-CR-OP system were located at 380 nm and 376 nm, respectively. Under optimum experimental conditions, the increased RRS intensities (ΔI) of these two systems were linear to CTS concentration in the range of 0.40-8.00 μg/ml and 0.05-1.00 μg/ml. Their limits of detection (LOD) were 44.81 ng/ml and 6.99 ng/ml, which indicated that the latter system was more sensitive than the former. In this work, the optimum conditions and the effects of some foreign substances on the determination were studied. In addition, the effect of the molecular weight of CTS and the reasons for the enhancement of resonance light scattering were discussed. Finally, these two methods were applied to the determination of chitosan in health products with satisfactory results.

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A simple and rapid method for direct determination of Al(III) based on the enhanced resonance Rayleigh scattering of hemin-functionalized graphene-Al(III) system

Cited by 11 publications

References 48 publications

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer‐Based Nanocomposites

A novel absorption spectrometric method, based on graphene nanomaterials, for detection of hepatocellular carcinoma-specific T lymphocyte cells

Resonance Rayleigh scattering methods for the determination of chitosan with Congo red as probe

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