A simple, optically induced electrokinetic method to concentrate and pattern nanoparticles

We demonstrate an optically induced ac electrokinetic technique that rapidly and continuously accumulates colloids on a parallel-plate electrode surface resulting in a crystalline-like aggregation. Electrothermal hydrodynamics produce a microfluidic vortex that carries suspended particles toward its center where they are trapped by local ac electrokinetic hydrodynamic forces. We characterize the rate of particle aggregation as a function of the applied ac voltage, ac frequency and illumination intensity. Hundreds of polystyrene particles (1.0 μm) suspended in a low conductivity solution (2.4 mS m −1 ) were captured at a range of voltages (5-20 V pp ) and frequencies (20-150 kHz) with an optical power of approximately 20 mW. This technique was not restricted to near infrared (1064 nm) illumination and was also demonstrated at 532 nm. The sorting capability of this technique was demonstrated with a solution containing 0.5 μm, 1.0 μm and 2.0 μm polystyrene particles. This dynamic optically induced technique rapidly concentrates, sorts and translates colloidal aggregates with a simple parallel-plate electrode configuration and can be used for a variety of lab-on-a-chip applications.

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“…The experimental image shows a concentration of over 500 1.0 μm particles. Illustration modified from [2].…”

Section: Introductionmentioning

confidence: 99%

“…Recently, we introduced an ac electrokinetic technique that can rapidly accumulate, translate and pattern micro-and nanoparticles and concentrate them on the surface of an electrode [1][2][3]. Rapid electrokinetic patterning (REP) is optically induced, offering dynamic control of the aggregation.…”

Section: Introductionmentioning

confidence: 99%

Optically induced electrokinetic concentration and sorting of colloids

Williams

Kumar

Green

et al. 2009

J. Micromech. Microeng.

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“…Rapid electrokinetic patterning (REP) is a hybrid technique that utilizes simultaneous application of a uniform AC electric field and an optical laser beam for manipulation of a diverse set of particles [26,58,[60][61][62][63]. While the two driving sources provide the electrokinetic effect and the optical effect, the combination of the two produces an additional electrothermal effect.…”

Section: Rapid Electrokinetic Patterningmentioning

confidence: 99%

“…This capability has been demonstrated in various experiments. Williams et al carried out particle manipulation in a variety of forms using REP [61][62][63]. Micro-sized colloids were rapidly trapped and configured into various shapes on an electrode surface by the optical landscapes produced by an Nd:YVO 4 laser under the application of a uniform electric field.…”

Section: Introductionmentioning

confidence: 99%

“…Based on this combination, particles are manipulated by separate mechanisms for each of the two driving sources and a new mechanism derived from the interaction of the two driving forces. Rapid electrokinetic patterning (REP) is an example of the hybrid manipulation technique [26,58,[60][61][62][63]. REP is a non-invasive manipulation technique that utilizes the simultaneous application of a uniform alternating current (AC) electric field and an optical laser beam.…”

Section: Introductionmentioning

confidence: 99%

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Microfluidic Technology for Cell Manipulation

Kwon

2018

Applied Sciences

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Featured Application: Microfluidic manipulation techniques not only improve the efficiency and reliability of biological/clinical analysis, but also further enable the development of a high-performance bioassay system. Abstract: Microfluidic techniques for cell manipulation have been constantly developed and integrated into small chips for high-performance bioassays. However, the drawbacks of each of the techniques often hindered their further advancement and their wide use in biotechnology. To overcome this difficulty, an examination and understanding of various aspects of the developed manipulation techniques are required. In this review, we provide the details of primary microfluidic techniques that have received much attention for bioassays. First, we introduce the manipulation techniques using a sole driving source, i.e., dielectrophoresis, electrophoresis, optical tweezers, magnetophoresis, and acoustophoresis. Next, we present rapid electrokinetic patterning, a hybrid opto-electric manipulation technique developed recently. It is introduced in detail along with the underlying physical principle, operating environment, and current challenges. This paper will offer readers the opportunity to improve existing manipulation techniques, suggest new manipulation techniques, and find new applications in biotechnology.

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Light‐Gated Manipulation of Micro/Nanoparticles in Electric Fields

Huang

Liang

Alsoraya

et al. 2020

Advanced Intelligent Systems

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The rapid development of micro/nanomanipulation technologies has opened unprecedented opportunities for the sorting, assembly, and actuation of biological and inorganic entities for applications ranging from live‐cell separation, drug screening, biosensing to micro/nanomachines and nanorobots. To this end, remarkable progress has been made in the development of efficient, precise, and versatile nanomanipulation techniques based on individual or combined chemical and physical fields. Among them, techniques that fuse light stimuli with electric (E) fields, have achieved impressive performance in the versatility, reconfigurability, and throughput in the manipulation of both biological and inorganic micro/nanoscale objects compared to those of many other manipulation techniques, by leveraging the strong optoelectric coupling effect of semiconductor materials. This work provides a review of various types of light‐gated electric manipulation systems – the working principles, experimental setups, limitations, applications, and future perspectives.

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A simple, optically induced electrokinetic method to concentrate and pattern nanoparticles

Cited by 62 publications

References 25 publications

Optically induced electrokinetic concentration and sorting of colloids

Optically induced electrokinetic concentration and sorting of colloids

Microfluidic Technology for Cell Manipulation

Light‐Gated Manipulation of Micro/Nanoparticles in Electric Fields

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