A Simple Strategy to Achieve Mussel‐Inspired Highly Effective Antibacterial Coating

Abstract

Although significant progress has been made in the preparation of mussel‐inspired antibacterial coatings, continual challenges still remain in pursuing more facile and simpler fabrication methods to construct more robust and effective coatings. In this study, quaternized catechol (QCat), which is synthesized via a simple quaternization reaction from two commercially available materials, 2‐chloro‐3′,4′‐dihydroxyacetophenone and N,N‐dimethyldodecylamine, is used as a reactive antimicrobial agent to fabricate mussel‐inspired antibacterial coatings. Specifically, QCat reacts with branched polyethyleneimine (PEI) in Tris‐HCl solution through a cross‐linking reaction between amino and catechol groups to form a homogeneous coating on various substrates via a simple co‐deposition process. The formed PEI/QCat coating exhibits highly effective antimicrobial activity against both Staphylococcus aureus and Escherichia coli and good adhesion on glass, metal, and plastic substrates. Such a simple fabrication process makes it a potential candidate for industrial and medical applications.

Antifouling and Antibacterial Polymer-Coated Surfaces Based on the Combined Effect of Zwitterions and the Natural Borneol

“…Bacterial adhesion and subsequent proliferation are often the initial steps leading to implantation failure. − To address these issues, numerous efforts have been directed toward developing biocide agents. A number of antibacterial agents that replace antibiotics, such as quaternary ammonium polymers, antimicrobial peptides, metal ions/particles, graphene, and so forth, − have also been utilized to prepare the effective antibacterial coatings. Most of these antibacterial materials were sterilized by fixing or releasing bactericides and exhibited highly efficient antibacterial activities; however, they did not possess the ability to inhibit bacteria from adhering to surfaces, which provides an opportunity for subsequent bacterial adhesion .…”

Robust Catechol Containing Cationic Waterborne Polyurethanes with Antibacterial, UV Protective, and Adhesive Properties

“…The molecular structure of emulsified polyurethane was further characterized by 1 H‐NMR to observe the quaternary ammonium structure and characteristic catechol structure of the neutralizer DBA, as shown in Figure 2d. After emulsion process, the peaks can be seen at 6.83–7.42 ppm, corresponding to the protons in the benzene ring [ 38 ] of the neutralizer DBA, displayed in the CWPU‐4 spectra but not in CWPU‐0, which was distinguished on account of different neutralizers. This result proved that the catechol structure in the neutralizer DBA was grafted to the polyurethane molecular chain via a simple neutralization reaction successfully.…”

Sustainable photocatalytic synthesis of hydrogen peroxide from catechol-formaldehyde resin microspheres modulated by nitrogen-doped carbon dots

“…Due to the strong adsorption and autooxidation-induced crosslinking of the catechol structure, CFR-140 microspheres can be combined with NCDs-220 containing a large number of amino groups in covalent and non-covalent interactions, such as hydrogen-bonding and charge-transfer interactions. 45,46 In the X-ray powder diffraction (XRD) pattern, the diffraction peak of NCDs-220 appeared at 2θ = 20°, which was identified as the (002) crystal face of graphitic carbon. 34 This result was consistent with that identified by TEM.…”