A Simplified Pharmacologic Erection Program for Patients with Spinal Cord Injury

Erectile dysfunction in spinal cord-injured men: different treatment options

“…Since that time, several reports have been published on the use of papaverine, or a combination of papaverine and phentalamine and more recently prostaglandin E 1 in men with SCI. 4,15,16 It should be noted that the dose for SCI was significantly lower than that needed for other etiologies of ED. In the present study, after ICI therapy, 90% of patients had normal erections according to IIEF-EF score and highly significant Reference value of testosterone ¼ 2.5-10 ng/ml.…”

Treatments for erectile dysfunction in spinal cord patients: alternatives to phosphodiesterase type 5 inhibitors? A review study

“…Mean time since SCL occurred varied from 6 months to 7.1 years. 23,36 The mean age was around 39 years (range 34.7-43.7). 23,36 Three authors included only incomplete lesions (B, C, D) according to the ASIA Impairment Scale grade (AIS).…”

“…Only a few authors included all levels and degrees of lesions according to the ASIA/AIS scale for all SCL patients. [23][24][25] To facilitate better understanding, results are reported by dividing the data into two groups: conservative versus surgical treatments.…”

“…[23][24][25][26][27] The International Index of Erectile Function questionnaire composed of 15 questions (IIEF-15) was the most common validated questionnaire used to evaluate EF pre-and post treatment. [28][29][30][31] The abridged 5-item version of the International Index of Erectile Function (IIEF-5) was utilized as well.…”

Neurogenic erectile dysfunction

“…A1-prostadil increases intracellular cAMP and leads to smooth muscle relaxation and penile erection [6]. Both Caverject and MUSE (intraurethral PGE,; Virus, Inc., Mountain View, CA, U.S.A.) have been used in patients with a wide variety of neurogenic ED, including patients with diabetes, MS, SCI, and those who have undergone radical prostatectomy [75][76][77][78][79][80][81]. The success rate of intracavernosal injection has been estimated as 73% in all patients, with the major side effects being potential prolonged erections and penile pain [82].…”