It is very important to study the filling gas ratio and the real-time change of halogen gas ratio for the performance optimization of GM tube. It is very time -and labor-saving to use the simulating software, but there are few reports about it. In this paper, based on Garfield++ software, the type and proportion of gas filling in GJ4105 GM tube are simulated, mainly for binary (neon + halogen) and ternary (neon + argon + halogen) gas filling. According to the dead time and signal amplitude of charge signal output by GM tube, the relationship between filling gas ratio and performance effect was studied, which provided technical basis for optimal design and subsequent improvement of halogen GM counter performance.