A Sleep Apnea Monitoring IC for Respiration, Heart-Rate, SpO<sub>2</sub> and Pulse-Transit Time Measurement Using Thermistor, PPG and Body-Channel Communication

Kim, Dong‐Hee; Lee, Eunseok; Kim, Ji‐Hwan; Park, Pangi; Cho, SeongHwan

doi:10.1109/jsen.2019.2950367

Cited by 12 publications

(4 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The measuring average length of the NREM-REM phases is one of the useful methods to analyze sleep quality. Several technologies exist for measuring sleep stage signals, for instance, EEG [122], EOG [123], acceleration [124], respiratory [125], and photoplethysmography [126]. The most informative of these methods is EEG because it shows that the alternation in brain waves follows the awake and sleep stages [127][128][129].…”

Section: Orexinsmentioning

confidence: 99%

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

Kniazkina

Dyachuk

2023

IJMS

View full text Add to dashboard Cite

Sleep–wake cycle disorders are an important symptom of many neurological diseases, including Parkinson’s disease, Alzheimer’s disease, and multiple sclerosis. Circadian rhythms and sleep–wake cycles play a key role in maintaining the health of organisms. To date, these processes are still poorly understood and, therefore, need more detailed elucidation. The sleep process has been extensively studied in vertebrates, such as mammals and, to a lesser extent, in invertebrates. A complex, multi-step interaction of homeostatic processes and neurotransmitters provides the sleep–wake cycle. Many other regulatory molecules are also involved in the cycle regulation, but their functions remain largely unclear. One of these signaling systems is epidermal growth factor receptor (EGFR), which regulates the activity of neurons in the modulation of the sleep–wake cycle in vertebrates. We have evaluated the possible role of the EGFR signaling pathway in the molecular regulation of sleep. Understanding the molecular mechanisms that underlie sleep–wake regulation will provide critical insight into the fundamental regulatory functions of the brain. New findings of sleep-regulatory pathways may provide new drug targets and approaches for the treatment of sleep-related diseases.

show abstract

Section: Orexinsmentioning

confidence: 99%

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

Kniazkina

Dyachuk

2023

IJMS

View full text Add to dashboard Cite

show abstract

“…They are primarily used to monitor cardiovascular health [4], facilitating the detection of heart rate variability [5], arrhythmias [6], and peripheral vascular diseases [4]. By analyzing the pulsatile component of the PPG signal, clinicians can evaluate blood flow and oxygen saturation [5], which is essential for managing conditions such as chronic obstructive pulmonary disease and sleep apnea [7]. Additionally, PPG plays a significant role in monitoring stress and mental health by assessing changes in heart rate [7] and blood volume in response to stress [8].…”

Section: Introductionmentioning

confidence: 99%

“…By analyzing the pulsatile component of the PPG signal, clinicians can evaluate blood flow and oxygen saturation [5], which is essential for managing conditions such as chronic obstructive pulmonary disease and sleep apnea [7]. Additionally, PPG plays a significant role in monitoring stress and mental health by assessing changes in heart rate [7] and blood volume in response to stress [8]. It is also widely used in fitness and wearable devices to monitor physical activity and overall health metrics.…”

Section: Introductionmentioning

confidence: 99%

A Low-Power High-Sensitivity Photocurrent Sensory Circuit with Capacitive Feedback Transimpedance for Photoplethysmography Sensing

Mohan,

Awwad,

Albastaki

et al. 2024

Sensors

View full text Add to dashboard Cite

This study presents an integrated analog front-end (AFE) tailored for photoplethysmography (PPG) sensing. The AFE module introduces a novel transimpedance amplifier (TIA) that incorporates capacitive feedback techniques alongside common drain feedback (CDF) TIA. The unique TIA topology achieves both high gain and high sensitivity while maintaining low power consumption. The resultant PPG sensor module demonstrates impressive specifications, including an input noise current of 4.81 pA/sqrt Hz, a transimpedance gain of 18.43 MΩ, and a power consumption of 68 µW. Furthermore, the sensory system integrates an LED driver featuring automatic light control (ALC), which dynamically adjusts the LED power based on the strength of the received signal. Employing 0.35 µm CMOS technology, the AFE implementation occupies a compact footprint of 1.98 mm × 2.475 mm.

show abstract

“…During heartbeat monitoring, light pulses with different wavelengths are used to noninvasively determine various physiological parameters. Typically, PPG measurement systems, such as pulse oximeters, include an optical sensor that can be easily attached to one of the patient's appendages (e.g., finger or earlobe) [20]. This optical sensor consists of a light-emitting diode (LED) and a photodetector.…”

Section: Introductionmentioning

confidence: 99%

Design and Implementation of a Multifunction Wearable Device to Monitor Sleep Physiological Signals

et al. 2020

View full text Add to dashboard Cite

We present a wearable device built on an Adafruit Circuit Playground Express (CPE) board and integrated with a photoplethysmographic (PPG) optical sensor for heart rate monitoring and multiple embedded sensors for medical applications—in particular, sleep physiological signal monitoring. Our device is portable and lightweight. Due to the microcontroller unit (MCU)-based architecture of the proposed device, it is scalable and flexible. Thus, with the addition of different plug-and-play sensors, it can be used in many applications in different fields. The innovation introduced in this study is that with additional sensors, we can determine whether there are intermediary variables that can be modified to improve our sleep monitoring algorithm. Additionally, although the proposed device has a relatively low cost, it achieves substantially improved performance compared to the commercially available Philips ActiWatch2 wearable device, which has been approved by the Food and Drug Administration (FDA). To assess the reliability of our device, we compared physiological sleep signals recorded simultaneously from volunteers using both our device and ActiWatch2. Motion and light detection data from our device were shown to be correlated to data simultaneously collected using the ActiWatch2, with correlation coefficients of 0.78 and 0.89, respectively. For 7 days of continuous data collection, there was only one instance of a false positive, in which our device detected a sleep interval, while the ActiWatch2 did not. The most important aspect of our research is the use of an open architecture. At the hardware level, general purpose input/output (GPIO), serial peripheral interface (SPI), integrated circuit (I2C), and universal asynchronous receiver-transmitter (UART) standards were used. At the software level, an object-oriented programming methodology was used to develop the system. Because the use of plug-and-play sensors is associated with the risk of adverse outcomes, such as system instability, this study heavily relied on object-oriented programming. Object-oriented programming improves system stability when hardware components are replaced or upgraded, allowing us to change the original system components at a low cost. Therefore, our device is easily scalable and has low commercialization costs. The proposed wearable device can facilitate the long-term tracking of physiological signals in sleep monitoring and related research. The open architecture of our device facilitates collaboration and allows other researchers to adapt our device for use in their own research, which is the main characteristic and contribution of this study.

show abstract

A Sleep Apnea Monitoring IC for Respiration, Heart-Rate, SpO₂ and Pulse-Transit Time Measurement Using Thermistor, PPG and Body-Channel Communication

Cited by 12 publications

References 33 publications

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

A Low-Power High-Sensitivity Photocurrent Sensory Circuit with Capacitive Feedback Transimpedance for Photoplethysmography Sensing

Design and Implementation of a Multifunction Wearable Device to Monitor Sleep Physiological Signals

Contact Info

Product

Resources

About

A Sleep Apnea Monitoring IC for Respiration, Heart-Rate, SpO2 and Pulse-Transit Time Measurement Using Thermistor, PPG and Body-Channel Communication

Cited by 12 publications

References 33 publications

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

Does EGFR Signaling Mediate Orexin System Activity in Sleep Initiation?

A Low-Power High-Sensitivity Photocurrent Sensory Circuit with Capacitive Feedback Transimpedance for Photoplethysmography Sensing

Design and Implementation of a Multifunction Wearable Device to Monitor Sleep Physiological Signals

Contact Info

Product

Resources

About

A Sleep Apnea Monitoring IC for Respiration, Heart-Rate, SpO₂ and Pulse-Transit Time Measurement Using Thermistor, PPG and Body-Channel Communication