A small-volume microcapillary rheometer

Salipante, Paul; Kuei, Steve; Hudson, Steven D.

doi:10.1007/s00397-022-01333-4

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…Several studies have proposed microcapillary rheometers that measure rheology with very small sample volumes over wide of shear rate ranges (10-10 5 s −1 ). [30][31][32] Although very precise, these require complex instrumentation.…”

Section: Introductionmentioning

confidence: 99%

Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis

Sarıyer,

Gill,

Needs

et al. 2023

Sens. Diagn.

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Section: Introductionmentioning

confidence: 99%

Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis

Sarıyer,

Gill,

Needs

et al. 2023

Sens. Diagn.

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“…Methods based on the use of microelectromechanical systems (MEMS) immersed in fluids have also been developed to extract the rheology of fluids [7][8][9][10]. Microfluidic rheometry has gained significant interest due to its ability to measure fluid properties using a small volume [11]. Optical coherence viscosimetry [12], surface light scattering on fluid interfaces [13][14][15][16] and drop oscillations [17][18][19] were also used to probe the rheology of liquids and polymer solutions.…”

Section: Introductionmentioning

confidence: 99%

Viscoelastic rheology of polymer solution probed by resonant thermal capillary fluctuation

Zhang,

Gorin,

Kellay

et al. 2023

Physics of Fluids

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We present a measurement of viscoelastic properties of polymer solutions using resonant thermal capillary fluctuations of the surface of a polymer solution droplet. The instantaneous deflection of a cantilever in contact with the drop surface allows for measuring the nanoscale thermal fluctuations of the interface. From the power spectral density of measured fluctuations, we determine the two components of the rheological (dynamic and elastic viscosity) response of the fluid. Our experimental results were compared with rheological measurements using a classical commercial rheometer. We find a good agreement between the two measurements. Our experiments allow to extend the range for dynamical measurements of rheological properties of the solutions up to 20 000 s−1. Furthermore, our method requires only a small volume of liquid (10 μl) to measure the viscosity and is thus suitable for measurements on precious liquids.

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Microfluidic techniques for mechanical measurements of biological samples

Salipante

2023

Biophysics Reviews

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The use of microfluidics to make mechanical property measurements is increasingly common. Fabrication of microfluidic devices has enabled various types of flow control and sensor integration at micrometer length scales to interrogate biological materials. For rheological measurements of biofluids, the small length scales are well suited to reach high rates, and measurements can be made on droplet-sized samples. The control of flow fields, constrictions, and external fields can be used in microfluidics to make mechanical measurements of individual bioparticle properties, often at high sampling rates for high-throughput measurements. Microfluidics also enables the measurement of bio-surfaces, such as the elasticity and permeability properties of layers of cells cultured in microfluidic devices. Recent progress on these topics is reviewed, and future directions are discussed.

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A small-volume microcapillary rheometer

Cited by 5 publications

References 37 publications

Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis

Time- and distance-resolved robotic imaging of fluid flow in vertical microfluidic strips: a new technique for quantitative, multiparameter measurement of global haemostasis

Viscoelastic rheology of polymer solution probed by resonant thermal capillary fluctuation

Microfluidic techniques for mechanical measurements of biological samples

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