A solitary fibrous tumor: an entity to consider in the diagnosis of liver masses

García, Irene Andaluz; Tavecchia, Mariana; Martín, Antonio Olveira

doi:10.17235/reed.2019.6433/2019

Cited by 3 publications

(1 citation statement)

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“…Notably, only a small number of patients develop paraneoplastic syndromes, such as hypertrophic osteoarthropathy and hypoglycemia ( 5 ). Hypertrophic osteoarthropathy is attributed to the overexpression of vascular endothelial growth factor ( 5 ), and hypoglycemia is caused by the overexpression of insulin-like growth factor 2( 23 ). A previous study demonstrated that the vast majority of SFTs are benign, and seldom recur or metastasize ( 24 ).…”

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confidence: 99%

Multidisciplinary collaboration for the successful treatment of a giant hepatic solitary fibrous tumor protruding into the thorax: A case report

et al. 2022

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Solitary fibrous tumors (SFTs) are composed of spindle cells and collagen fibers, and these form rare mesenchymal tumors. SFTs are most frequently observed in intrathoracic sites; however, they may also occur in extrathoracic sites, such as the liver. Unlike the hepatic SFTs (HSFTs) reported in the literature, the SFT detailed in the present case report was a large tumor that originated from the liver, with a dumbbell-shaped growth through the diaphragm into the right thoracic cavity. This posed substantial challenges in both diagnosis and treatment. Thus, the present report outlines the findings of a multidisciplinary team meeting that was used to discuss and develop an optimal and personalized treatment strategy for the patient. Transhepatic arterial embolization was performed to block the major arterial blood supply to the tumor in order to reduce its size. Subsequently, the tumor was fully resected, following the collaboration of the experienced hepatobiliary and thoracic surgeons. Following surgery, the abdominal distension experienced by the patient ceased, and no tumor recurrence was detected at the 1-year follow-up. In conclusion, due to limited previous reports of HSFT treatment using multidisciplinary collaboration, the present study outlined the treatment used for this specific tumor type, and the corresponding literature was reviewed.

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