A Strategy for Trapping Molecular Guests in MOF-5 Utilizing Surface-Capping Groups

Homan, Rick A.; Hendricks, Dalton S.; Rayder, Thomas M.; Thein, U Shwe; Fossum, Katherine J.; Vázquez, Adriana P. Claudio; Yan, Jingjing; Grimm, Ronald L.; Burdette, Shawn C.; MacDonald, John C.

doi:10.1021/acs.cgd.9b00818

Cited by 8 publications

(2 citation statements)

References 24 publications

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“…Meanwhile, the symmetric arms of CV are 8.5 Å in length, which implies that it will not be too large to cross the channels or pores of host materials, like MOFs. [ 34 ]…”

Section: Introductionmentioning

confidence: 99%

Co‐Quenching Effect between Lanthanum Metal–Organic Frameworks Luminophore and Crystal Violet for Enhanced Electrochemiluminescence Gene Detection

Gao

Wei

et al. 2021

Small

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Exploring new electrochemiluminescence (ECL) luminophores to construct high‐efficiency sensing systems is always a hot direction for developing ECL sensors. Compared with other luminophores, metal–organic frameworks (MOFs) exhibit high mass transfer ability for accelerating the reactivity in its pore channels, which is conducive to improving the performance of ECL sensors. In this work, La3+‐BTC MOFs (LaMOFs) are prepared as the highly active reactor and novel ECL luminophore. On this basis, a novel co‐quenching effect mechanism is proposed based on double‐stranded DNA (dsDNA) triggered cooperation between LaMOFs and crystal violet (CV) molecules. Under the confined pore channels of LaMOFs, CV can play an important role as the photon‐acceptor due to the matched absorption spectrum with the ECL spectrum of LaMOFs, and the electron‐acceptor on account of its lowest unoccupied molecular orbital level. Based on the proposed co‐quenching effect mechanism, a constructed ECL gene sensor shows good assay performance toward p53 gene in the detection range of 1 pm to 100 nm with a detection limit of 0.33 pm. The co‐quenching effect integrating LaMOFs with CV is expected to be a versatile approach in the construction of ECL gene sensor, which has good prospect in expanding the application range of ECL technology.

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“…Meanwhile, the symmetric arms of CV are 8.5 Å in length, which implies that it will not be too large to cross the channels or pores of host materials, like MOFs. [ 34 ]…”

Section: Introductionmentioning

confidence: 99%

Co‐Quenching Effect between Lanthanum Metal–Organic Frameworks Luminophore and Crystal Violet for Enhanced Electrochemiluminescence Gene Detection

Gao

Wei

et al. 2021

Small

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“…In the following, MOF surfaces with protruding phenyl or benzoic acid linkers will be identified by the suffix "phenyl" or "benzoic", and the surface model of CAU-10 with accessible pores on the surface in Figure 2e Although phenyl linkers will not be present after synthesizing MOF-5, as this would require the dissociation of the BDC linker during synthesis, capping reagents or modulators are often used to control the crystal size and hence the nature of the external surface. 26 The modification of the external surface of MOF-5 in the literature comprises for instance the use of capping reagents such as triphenylacetic acid, diphenylacetic acid, trimethylacetic acid, acetic acid, diisopropylethylamine and triethylamine by Homan et al, 27 or 4-decylbenzoic acid by Zacher et al 26 Benzoic acid is another common capping reagent 28−30 and while it has, to the best of our knowledge, not yet been used to modify the external surface of MOF-5, this approach allows the formation of surface models with very different structures for contact angle simulations.…”

Section: ■ Introductionmentioning

confidence: 99%

Do Internal and External Surfaces of Metal–Organic Frameworks Have the Same Hydrophobicity? Insights from Molecular Simulations

et al. 2020

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Reliable information on the hydrophobicity of porous materials is important in the design of many catalytic and separation processes. In general, hydrophobicity is assessed by measuring the contact angle of water (external surface) or the adsorption isotherm of water (internal surface). However, it is not clear how these different assessments are related. In this paper, molecular dynamics simulations of microscopic water droplets on the external surfaces of metal–organic frameworks are used to investigate the influence of the surface nature and hydrophobicity on the contact angle. The metal–organic frameworks MOF-5 and CAU-10 were modeled with external surfaces of different hydrophobicities, while the internal surface was maintained. It was observed that microscopic droplets orientate their spreading to the nature of the external surfaces. Comparing the simulated contact angles and adsorption isotherms confirms the necessity to distinguish between internal and external hydrophobicity.

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Thoughts on the Rational Design of MOF‐Guest Interactions for Future Intelligent Materials

Asselin,

Harvey

2024

Small Methods

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The MOF‐guest relationship is broken down in elementary phases, descriptors, and parameters. These descriptors and parameters allow precise descriptions of processes, whether they occur at the point when the guest enters the MOF, during the stay, or at the point of exiting. Description of these three phases is possible according to the location of the guest inside the MOF, the activity between MOF and guest, whether stimuli can be used, and whether a selective action can be exercised. The vocabulary provided herein can be useful to better formulate requirements when designing host‐guest interactions in, and building new classes of, intelligent materials.

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A Strategy for Trapping Molecular Guests in MOF-5 Utilizing Surface-Capping Groups

Cited by 8 publications

References 24 publications

Co‐Quenching Effect between Lanthanum Metal–Organic Frameworks Luminophore and Crystal Violet for Enhanced Electrochemiluminescence Gene Detection

Co‐Quenching Effect between Lanthanum Metal–Organic Frameworks Luminophore and Crystal Violet for Enhanced Electrochemiluminescence Gene Detection

Do Internal and External Surfaces of Metal–Organic Frameworks Have the Same Hydrophobicity? Insights from Molecular Simulations

Thoughts on the Rational Design of MOF‐Guest Interactions for Future Intelligent Materials

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