A Study of Impaired Glucose Tolerance Test in Pulmonary Tuberculosis

Abstract

The link between Diabetes mellitus & Tuberculosis has been recognizing for centuries. Recently Tuberculosis has re-emerged as a major health concern. There is growing evidence that Diabetes mellitus with Tuberculosis may affect disease presentation and treatment. The Tuberculosis also influences glucose intolerance and influences the glycaemic control in the people with Diabetes mellitus. Approximately 2 Million persons worldwide died of Tuberculosis and 9 Million become infected each year. (CDC, 2007) 1. With the convergence of tuberculosis and diabetes Mellitus epidemic, co-affliction with the two diseases is on the rise. The observational study was conducted with 100 patients. The patients with Pulmonary Tuberculosis sputum positive/negative with radiological lesions was admitted in medicine wards of our hospital between years 2009-2011. The aim of our study is to find out the prevalence of GTT in patients of Pulmonary Tuberculosis Age, sex distribution of impaired Glucose Tolerance Test (GTT) in Patients with pulmonary tuberculosis and study the correlation between impaired GTT with Sputum positivity and also radiological extent of disease. The patients were subjected to oral GTT and results were evaluated according to the WHO criteria and the statistical analysis was done to determine the P value and significance on the basis Chi-square test. The results found in the studied patient were that prevalence of abnormal GTT in Pulmonary Tuberculosis patients was found to be 22% (P=0.07). Abnormal GTT was more common in males as compared to females and this was found to be significant (P=0.692). Sputum positive Pulmonary Tuberculosis is strongly associated in patients with abnormal GTT (P=0.03), and bilateral lung involvement was more common among Pulmonary Tuberculosis patients with abnormal GTT.

The Association of Pulmonary Tuberculosis, Abnormal Glucose Tolerance, and Type 2 Diabetes Mellitus: A Hospital-Based Cross-Sectional Study

“…TB patients with T2DM were found predisposed to infection relapses, treatment failures, increased mortality, delayed mycobacterial clearance as observed by previous studies [ 7 - 9 ]. The IGT may occur transiently during pulmonary TB owing to the stress of prevailing infection and it has been shown to improve following effective anti-tubercular therapy [ 10 ]. Previous studies have shown a high prevalence of abnormal glucose tolerance (GT) in TB patients with rates ranging from 2% to 41% after OGTT [ 11 ].…”

Report of metallic shield bug, Scutellera perplexa (Fabricius) (Scutelleridae: Hemiptera) on Phalsa (Grewia asiatica L.) from Gujarat, India

“…The avoidable loss is more due to insect pests. Lakra and Bhatti (1985) reported that as many as 130 species of insect pests on ber in India, but only few species have attained the status of the pest and cause considerable damage. Jothi and Tandon (1995); Patil and Patil (1996); Kavitha et al, (2002); Balikai (1999); Haldhar et al, 2016 andKaruppaiah et al, 2010 recorded seveal insect-pests and non insect pests on ber in Karnataka, Andra Pradesh and Rajasthan Apart from several important insect pests causing damage to ber, one such insect pest that feeds on ber leaf is Tarucus indica Evans (Lycaenidae: Lepidoptera).…”

Behavioral assays of cotton leaf folder, Sylepta derogata (Fabricius) (Lepidoptera: Crambidae) on different host plants

“…The avoidable loss is more due to insect pests. Lakra and Bhatti (1985) reported that as many as 130 species of insect pests on ber in India, but only few species have attained the status of the pest and cause considerable damage. Jothi and Tandon (1995); Patil and Patil (1996); Kavitha et al, (2002); Balikai (1999); Haldhar et al, 2016 andKaruppaiah et al, 2010 recorded seveal insect-pests and non insect pests on ber in Karnataka, Andra Pradesh and Rajasthan Apart from several important insect pests causing damage to ber, one such insect pest that feeds on ber leaf is Tarucus indica Evans (Lycaenidae: Lepidoptera).…”