The link between Diabetes mellitus & Tuberculosis has been recognizing for centuries. Recently Tuberculosis has re-emerged as a major health concern. There is growing evidence that Diabetes mellitus with Tuberculosis may affect disease presentation and treatment. The Tuberculosis also influences glucose intolerance and influences the glycaemic control in the people with Diabetes mellitus. Approximately 2 Million persons worldwide died of Tuberculosis and 9 Million become infected each year. (CDC, 2007) 1. With the convergence of tuberculosis and diabetes Mellitus epidemic, co-affliction with the two diseases is on the rise. The observational study was conducted with 100 patients. The patients with Pulmonary Tuberculosis sputum positive/negative with radiological lesions was admitted in medicine wards of our hospital between years 2009-2011. The aim of our study is to find out the prevalence of GTT in patients of Pulmonary Tuberculosis Age, sex distribution of impaired Glucose Tolerance Test (GTT) in Patients with pulmonary tuberculosis and study the correlation between impaired GTT with Sputum positivity and also radiological extent of disease. The patients were subjected to oral GTT and results were evaluated according to the WHO criteria and the statistical analysis was done to determine the P value and significance on the basis Chi-square test. The results found in the studied patient were that prevalence of abnormal GTT in Pulmonary Tuberculosis patients was found to be 22% (P=0.07). Abnormal GTT was more common in males as compared to females and this was found to be significant (P=0.692). Sputum positive Pulmonary Tuberculosis is strongly associated in patients with abnormal GTT (P=0.03), and bilateral lung involvement was more common among Pulmonary Tuberculosis patients with abnormal GTT.

ABSTRACT:The present study is designed to find out frequency of various histological patterns of breast lesions in patients attending Chhattisgarh Institute of Medical Sciences (CIMS), a teaching institute in Bilaspur Chhattisgarh and their biopsy samples studied in department of pathology. A retrospective series study was conducted on 335 cases of breast lesions, reported from 2003 to 2014. Mean age of the subjects was 49.65 years with standard deviation 12.06 years, ranging from 12 to 75 years. In a total 335 cases, 40(11.94%) were non-neoplastic and 295(88.06%) were neoplastic. Among neoplastic lesions, 180(53.73%) were benign, 02(0.59%) borderline and 113(33.73%) found malignant. The commonest non-neoplastic lesion was fibrocystic disease of breast followed by fibroadenosis and sclerosing adenosis. Neoplastic lesions were more common than non-neoplastic lesions. Among histological types of breast tumours, fibroadenoma dominated the other types. Thus commonest benign tumour was fibroadenoma followed by phyllodes tumour and commonest malignant was infiltrating duct carcinoma followed by medullary carcinoma. The commonest borderline tumour was phyllodes tumour with borderline changes.

INTRODUCTION:Cancer of the breast is among the commonest of human cancers throughout the world. The incidence of breast cancer in Indian women is much lesser than the counterparts in industrialized nations. OBJECTIVE: This study is designed to find out prevalence of breast cancer in patients attending Chhattisgarh Institute of Medical Sciences (CIMS), a teaching institute in Bilaspur Chhattisgarh. MATERIAL AND METHODS: The biopsy samples of all patients were received and studied in department of pathology. A retrospective series study was conducted on 316 cases of breast tumours, reported from March 2003 to August 2015. RESULTS AND OBSERVATIONS: Mean age of the subjects is 45 years with standard deviation 12.06 years ranging from 12 to 75 years. Among 316 neoplastic lesions, 198 (62.66%) were found benign, 02 (0.63%) borderline and 116 (36.71%) were malignant. Among histological types of malignant breast tumours, infiltrating duct carcinoma dominated, and is followed by medullary carcinoma. CONCLUSION: Mean age of our female breast cancer patients was found to be lower compared to the western world, with an average difference of one decade. A majority of the patients were from a rural background and had a longer duration of symptoms compared to urban patients. Lump in the breast was a dominant symptom. Familial breast cancer was uncommon.

BACKGROUND: Fine needle aspiration cytology is a well-established simple, safe technique among diagnostic tests for evaluation of thyroid lesions. It helps for the preoperative diagnosis of benign and malignant lesions, thus minimizing and preventing the unwanted surgeries. OBJECTIVE: The aim of this retrospective study is to classify various cytomorphological lesions of the thyroid swellings in our setup & to know the age and sex incidence. METHOD: A retrospective study of 506 patients was conducted from January 2003 to December 2013 in pathology department of our hospital, Chhattisgarh Institute of Medical Sciences, Bilaspur. Fine needle aspiration of all cases was done after detailed clinical history, physical examination and thyroid function test. Then lesions were classified cytomorphologically. Age and sex incidence was calculated. RESULTS: FNAC results were classified as inadequate material, non-neoplastic, neoplastic and malignant. Out of total 506 cases studied. 416(82.2%) were non neoplastic 64(12.6%) were neoplastic 17(3.35%) were malignant lesions and 9(1.77%) cases were inadequate material. Age and sex incidence was calculated. Thyroid lesions showed female predominance, out of 506 cases, 428 were females and 78 were males. Commonest malignancy was papillary carcinoma of thyroid (7 cases). CONCLUSION: FNAC is a safe, simple less expensive widely accepted outpatient procedure for diagnosis of thyroid lesions. It also helps to avoid unwanted surgical interventions in patients with benign lesions.

The present study examined the patterns of sinonasal masses in biopsies received in department of pathology of Govt. CIMS, Bilaspur which is a tertiary care hospital of central eastern region of India and represents a tribal belt. During the study period, 91 biopsied reported were retrieved from the records and results analyzed. OBJECTIVE: This study is designed to find out patterns of benign lesions of nasal mass in patients attending Chhattisgarh Institute of Medical Sciences (CIMS), a teaching institute in Bilaspur Chhattisgarh. MATERIAL AND METHODS: 91 nasal biopsy records of March 2003 to August 2015 were reviewed. All the biopsy samples of patients were received and studied in department of pathology. RESULTS AND OBSERVATIONS: Average age of subjects reported as non-neoplastic lesions is found 19.69 years with standard deviation of 9.44, ranging from 6 to 47 years. Among 75 nonneoplastic lesions, 63 (84.00%) reported as rhinosporidiosis, 10(13.33%) non-specific inflammatory polyp and 2 were (2.67%) tuberculosis. CONCLUSION: Rhinosporidiosis encountered as most common non-neoplastic lesion and most patients affected were in younger age groups. The study concluded with the exceptionally higher prevalence of rhinosporidiosis observed in this region.