A study of infectious intestinal disease in England: risk factors associated with group A rotavirus in children

Abstract

SUMMARYObjecti e : To identify risk factors for infectious intestinal disease (IID) due to rotavirus group A in children aged under 16 years. Methods : Case-control study of cases of IID with rotavirus infection presenting to general practitioners (GPs) or occurring in community cohorts, and matched controls. Results : There were 139 matched pairs. In children under 16 years the following risk factors were significantly associated with rotavirus IID : living in rented council housing (adjusted OR l 3n78, P l 0n022), accommodation with more than five rooms (OR l 0n72, P l 0n002), contact with someone ill with IID (OR l 3n45, P 0n001). Some foods were associated with decreased risk. In infants, bottle feeding with or without breast feeding was associated with increased risk (OR l 9n06, P 0n05). Conclusions : Contact with persons with IID, living in rented council housing and accommodation with fewer rooms, were significant risk factors for sporadic rotavirus IID in children whereas breast feeding is protective in infants.

Haze is an important medium for the spread of rotavirus

“…The positive rate was higher than that of developed countries, such as England (14.3%) (Sethi et al, 2001); lower than that of some developing countries, such as Thailand (30%) (Chieochansin et al, 2016) and India (23%) (Namjoshi et al, 2014); and similar to the positive rate of rotavirus detection in Sudan (16%) (Magzoub et al, 2013). The danger to males was higher, and the ratio of infected males to females was 1.6:1.…”

“…Cumulative relative risks for temperature and air pollutants associated with the rotavirus infection rate using the DLNM model, which controlled for the effects of holiday effects, relative humidity, day of the week and long-term trends. conducted in England and Wales (Sethi et al, 2001), if an infection is transmitted indoors, one possible interpretation for the cold weather effect on rotavirus infections is that low ambient temperatures encourage individuals to stay indoors, thereby increasing their exposure to contaminated air and surfaces.…”

Temperature-dependent transmission of rotavirus in Great Britain and The Netherlands

“…In England and Wales, significant risk factors for rotavirus infection include contact with persons with rotavirus infection, living in rented public housing and accommodation with fewer rooms (Sethi et al 2001). If infection is transmitted indoors by individuals living in close proximity to each other (i.e.…”

Does population mixing measure infectious exposure in children at the community level?

“…These measures were included in the study because associations between deprivation and respiratory infections [20] and infectious intestinal diseases [21] have been reported before and previous studies involving childhood leukaemia have examined the number of persons [22] and population density [23,24]. These measures are potentially critical for defining infection dynamics [25].…”