We consider pressure-driven, steady state Poiseuille flow in straight channels with various crosssectional shapes: elliptic, rectangular, triangular, and harmonic-perturbed circles. A given shape is characterized by its perimeter P and area A which are combined into the dimensionless compactness number C = P 2 /A, while the hydraulic resistance is characterized by the well-known dimensionless geometrical correction factor α. We find that α depends linearly on C, which points out C as a single dimensionless measure characterizing flow properties as well as the strength and effectiveness of surface-related phenomena central to lab-on-a-chip applications. This measure also provides a simple way to evaluate the hydraulic resistance for the various shapes.