A Study of Naturally Acquired Canine Babesiosis Caused by Single and Mixed<i>Babesia</i>Species in Zambia: Clinicopathological Findings and Case Management

Nalubamba, King S.; Mudenda, Ntombi B.; Namwila, Mwaka Mwangala; Mulenga, Chilufya Susan; Bwalya, Eugene C; M’kandawire, Ethel; Saasa, Ngonda; Hankanga, Careen; Oparaocha, Elizabeth; Simuunza, Martin

doi:10.1155/2015/985015

Cited by 24 publications

(34 citation statements)

References 43 publications

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“…Decreased Hb level of the present study was in agreement with report of (Emily et al, 1925;Lobetti and Schoemana, 2001;Machado et al, 2002;Castro et al, 2004;Mali et al, 2006, Niwetpathomwat et al, 2006Ogunkoya et al, 2006;Helens, 2008;Kohn et al, 2008;Gunseelan et al, 2009;Turkar et al, 2009;Sharma et al, 2010;Qadir et al, 2011;Sarma et al, 2011;Shah et al, 2011;Wadhwa et al, 2011;Andoni et al, 2012;Dixit et al, 2012;Srikala et al, 2012;Bhardwaj, 2013;Bhojane et al, 2013;Konar, 2013 andReddy et al, 2014). TEC level was decreased in accordance with (Oliveira, 2000;Machado, 2002;Castro et al, 2004;Helens, 2008;Chattha et al, 2009;Gunseelan et al, 2009;Turkar et al, 2009;Qadir et al, 2011;Sarma et al, 2011;Andoni et al, 2012;Konar, 2013 andNalubamba et al, 2015).…”

Section: Haematological Profilesupporting

confidence: 70%

Etiopathology and Haematobiochemical Alteration in the Anaemic Dogs of in and Around Anand Region, Gujarat

Tandel¹,

Jani²,

Bilwal³

et al. 2019

JAR

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The present research work was undertaken to assess the etiopathology and haematobiochemical alterations in anemic dogs of Anand region, Gujarat irrespective of their age, sex and breed. Total 78 dogs were screened for anemia and blood samples were collected from a 51 anemic dogs of Anand region of Gujarat to identify etiopathology and haematobiochemical parameters alterations. Statistical analysis, interpretation, different etiology and comparison of haematobiochemical alteration with scientific literature were carried out to understand pathophysiology of disease. Amongst 78 of 51 dogs, incidence of anemia was recoded 65.38 per cent in which highest was due to liver disorders (23.53%). Incidence of anemia was observed higher in in adult group (58.83%) as well as in male (52.94%). Most clinical variants of anemic dogs showed pale mucous membrane (86.27%), hypothermia (68.63%), tachycardia (70.59%), tachypnea (74.51%) and increased capillary refilling time (64.71%). Haematological indices of anemic dogs revealed Hb, TEC, PCV, MCH, MCHC and MCV decreased significantly (p<0.01), whereas TLC increased significantly (p<0.05) as compare to healthy dogs. Serum biochemistry revealed significantly (p<0.01) increased BUN, Creatinine, Glucose, AST and ALT levels as well as decreased in total protein level in anemic case as compare to healthy ones. Different etiological factors for developing in anemia in dogs as well as hematobiochemical alterations are mentioned, which will be useful for further detailed investigations and therapeutic management.

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Section: Haematological Profilesupporting

confidence: 70%

Etiopathology and Haematobiochemical Alteration in the Anaemic Dogs of in and Around Anand Region, Gujarat

Tandel¹,

Jani²,

Bilwal³

et al. 2019

JAR

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“…[ 37 ], and Nalubamba et al . [ 38 ]. Hb and TEC levels could be due to epistaxis, petechial hemorrhages, direct mechanical disruption caused by parasite as it leaves red blood cells, intravascular hemolysis, and immune-mediated or non-immune mediated destruction of red blood cells or due to severe anemia.…”

Section: Resultsmentioning

confidence: 99%

Clinicopathological alterations in naturally occurring Babesia gibsoni infection in dogs of Middle-South Gujarat, India

2017

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Aim:The present research work was undertaken to describe various clinical signs and hematobiochemical alterations in dogs affected with Babesia gibsoni.Materials and Methods:Blood smears from a total of 79 suspected dogs of Anand region as well as Surat region of Gujarat state (India) were screened for detection of intraerythrocytic piroplasm of small form of Babesia. Diagnosis was made on the basis of clinical signs and demonstration of B. gibsoni organism in Giemsa-stained thin blood smears. The clinical signs were recorded at the time of presentation, and blood samples were subjected to estimation of hematobiochemical parameters by auto hematology analyzers at College of Veterinary Science and Animal Husbandry, Anand. Statistical analysis, interpretation, and comparison of hematobiochemical changes with scientific literature were carried out to understand the pathophysiology of the disease.Results:Out of 79 dogs, 16 were positive for naturally occurring babesiosis based on the presence of intraerythrocytic piroplasm of small form of Babesia in blood smears. The clinical cases were manifested by wide variety of non-specific clinical signs. The hematological evaluation revealed that the mean values of hemoglobin and total erythrocyte counts in dogs with babesiosis decreased significantly (p<0.01) in comparison to healthy dogs. Among differential leukocyte count, mean values of neutrophils and eosinophils increased while lymphocytes decreased (p<0.01) in dogs with babesiosis in comparison to healthy dogs. Serum biochemistry revealed increase (p<0.01) value of alkaline phosphatase, alanine aminotransferase, aspartate aminotransferase, and globulin as well as decrease in albumin levels (p<0.05) in dogs with babesiosis as compared to healthy dogs.Conclusion:B. gibsoni is having multisystemic effects with atypical hematobiochemical changes in dog are discussed here, which would aid new insights in diagnosis of disease.

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“…Canine babesiosis is caused by various species in the genus Babesia which have been classi ed as either small or large piroplasms based on microscopic appearance (4).Babesia parasites cause a debilitating illness in dogs that compromises their welfare and reduces their capacity to carry out their role in society (13). Clinical signs of canine babesiosis include fever, tachycardia, lethargy, hemolytic anemia, anorexia, vomiting, jaundice, pallor of mucus membranes amongst others (35,44). The severity of illness is determined by among other factors, the species of Babesia causing infection with B.canis rossi known to result in the most serious disease (14).…”

Section: Introductionmentioning

confidence: 99%

Phylogenetic Relationship of Babesia Species Infecting Dogs from Select Regions of Kenya

Ngoka

Mbogo

Kyallo

et al. 2020

Preprint

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There are over 100 Babesia species known to infect vertebrates with some of them being zoonotic. Local dog keeping practices enable extensive and intimate interactions between dogs, livestock, wildlife, and their human owners, thus allowing the possibility of dogs to act as hosts for zoonotic parasites.Canine babesiosis, known to occur in Kenya causes a severe and debilitating illness in dogs which compromises their welfare and capacity to carry out their role in society. Published data on Babesia species circulating among dogs in Kenya is limited. Improved control measures such as vaccines are required against the disease.The study design was descriptive and sampling opportunistic. A total of 143 whole blood samples were collected from domestic dogs in Nakuru, Nairobi and Mombasa counties. Total genomic DNA was extracted from each of the samples and screened for Babesia parasites using diagnostic PCR. Babesia species were identified through bioinformatic analysis of Sanger sequences.A total of 13 samples were positive for Babesia species (95% C.I is 0.0437 to 0.1381). Two were positive for Babesia canis vogeli, eleven were positive for Babesia canis rossi.77% of the Babesia positive samples were from Nairobi county.The study confirmed that molecular methods can be utilized to detect the presence of Babesia species circulating among dogs in Kenya.85% of the Babesia positive samples were Babesia canis rossi which causes the most severe form of canine babesiosis. Results of the bioinformatic analysis indicate 98.29% to 99.52% sequence identity to Babesia canis rossi obtained from black-backed jackals (Canis mesomelas).Babesia canis vogeli although primarily known as a domestic dog parasite has been shown capable of infecting both domestic and wild felines. This demonstrates the capacity of dogs to serve as hosts for pathogens from wildlife and vice versa.

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A Study of Naturally Acquired Canine Babesiosis Caused by Single and MixedBabesiaSpecies in Zambia: Clinicopathological Findings and Case Management

Cited by 24 publications

References 43 publications

Etiopathology and Haematobiochemical Alteration in the Anaemic Dogs of in and Around Anand Region, Gujarat

Etiopathology and Haematobiochemical Alteration in the Anaemic Dogs of in and Around Anand Region, Gujarat

Clinicopathological alterations in naturally occurring Babesia gibsoni infection in dogs of Middle-South Gujarat, India

Phylogenetic Relationship of Babesia Species Infecting Dogs from Select Regions of Kenya

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