2013
DOI: 10.7860/jcdr/2013/6019.3454
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A Study of Oxidative Stress Biomarkers and Effect of Oral Antioxidant Supplementation in Severe Acute Malnutrition

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Cited by 21 publications
(25 citation statements)
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“…Loss of membrane integrity, in case of mitochondria, undermine the efficiency with which the electron transport chain converts reducing equivalents to ATP, thus further aggravating the adverse effect of already reduced energy intake in malnourished children. The high levels of MDA are in agreement with those of other studies carried out by Khare Perampalli, Bosnak and Ghone et al [6][7][8] Catal F et al and Anuradha J et al reported that significantly increased level of serum MDA in patients with malnutrition as compared to controls. 9,10 In such condition, depletion of endogenous antioxidants may be expected.…”
Section: Discussionsupporting
confidence: 82%
“…Loss of membrane integrity, in case of mitochondria, undermine the efficiency with which the electron transport chain converts reducing equivalents to ATP, thus further aggravating the adverse effect of already reduced energy intake in malnourished children. The high levels of MDA are in agreement with those of other studies carried out by Khare Perampalli, Bosnak and Ghone et al [6][7][8] Catal F et al and Anuradha J et al reported that significantly increased level of serum MDA in patients with malnutrition as compared to controls. 9,10 In such condition, depletion of endogenous antioxidants may be expected.…”
Section: Discussionsupporting
confidence: 82%
“…The increased oxidative stress maintained by different antioxidant system (ascorbic acid, vitamin-E, SOD and so forth) and this antioxidants status altered in different uncontrolled disease condition [29][30][31][32]. Ascorbic acid, an antioxidant, has negative correlation with the major depression is a finding well-established [33].…”
Section: Discussionmentioning
confidence: 95%
“…It acts as reactive oxygen species scavenger, thus eliminates the reactive oxygen species and maintains the oxidative valance [36]. Its activity altered in numbers of diseases [29,30,37]. SOD activity found to be decreased in different depressive animal model [38,39].…”
Section: Discussionmentioning
confidence: 99%
“…However, phenolic compounds limit lipid oxidation (Siriamornpun, Tang, Khawanit & Kaewseejan, 2016) and thereby, reduce rancidity and enhance storage stability. Malnutrition can cause an increase in oxidative stress which could be alleviated by the consumption of a diet rich in antioxidants (Ghone et al, 2013).…”
Section: Total Phenolic Content (Tpc) Ferric Reducing Antioxidant Pomentioning
confidence: 99%