A study of prostate delineation referenced against a gold standard created from the visible human data

Gao, Z; Wilkins, David E.; Eapen, Libni; Morash, Christopher; Wassef, Youssef; Gerig, L

doi:10.1016/j.radonc.2007.08.001

Cited by 74 publications

(58 citation statements)

References 25 publications

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“…The variation of CTV volumes is slightly larger than previous studies on HCTs (12,13). The mean standard deviation of COM among different observers for 5 patient CBCT images were 0.7, 1.8 and 2.8 mm in Right-Left, Posterior-Anterior, and SuperiorInferior direction, respectively.…”

Section: Discussioncontrasting

confidence: 52%

Quantitative Evaluation of Cone Beam Computed Tomography in Target Volume Definition for Offline Image Guided Radiation Therapy of Prostate Cancer

Wang

Yan

2008

International Journal of Radiation Oncology*Biology*Physics

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Section: Discussioncontrasting

confidence: 52%

Quantitative Evaluation of Cone Beam Computed Tomography in Target Volume Definition for Offline Image Guided Radiation Therapy of Prostate Cancer

Wang

Yan

2008

International Journal of Radiation Oncology*Biology*Physics

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“…This is done by adding a margin to the CTV, which also includes uncertainties related to patient setup errors and prostate position error caused by interfraction movement and by intrafraction movement. However, the benefit of using image registration in prostate cancer radiotherapy is that it enables target delineation in MR, which has been shown to reduce the delineated volume by about 30%–40% 1 , 2 , 3 and has the potential to reduce long‐term toxicity (28) . The interfraction movement and intrafraction movement of the prostate can be reduced if the prostate is tracked continuously during all treatments.…”

Section: Discussionmentioning

confidence: 99%

“…However, studies have shown that a delineation of the clinical target volume (CTV) using CT leads to an overestimation of the CTV. CTVs up to 40% larger have been found on CT when compared to using magnetic resonance (MR) for CTV delineation 1 , 2 , 3 . As a consequence, MR imaging is commonly used for accurate soft‐tissue delineation of the prostate as the CTV and CT images are used for radiation dose calculations.…”

Section: Introductionmentioning

confidence: 99%

Comparison of manual and automatic MR‐CT registration for radiotherapy of prostate cancer

Korsager

Carl

Østergaard

2016

J Applied Clin Med Phys

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In image‐guided radiotherapy (IGRT) of prostate cancer, delineation of the clinical target volume (CTV) often relies on magnetic resonance (MR) because of its good soft‐tissue visualization. Registration of MR and computed tomography (CT) is required in order to add this accurate delineation to the dose planning CT. An automatic approach for local MR‐CT registration of the prostate has previously been developed using a voxel property‐based registration as an alternative to a manual landmark‐based registration. The aim of this study is to compare the two registration approaches and to investigate the clinical potential for replacing the manual registration with the automatic registration. Registrations and analysis were performed for 30 prostate cancer patients treated with IGRT using a Ni‐Ti prostate stent as a fiducial marker. The comparison included computing translational and rotational differences between the approaches, visual inspection, and computing the overlap of the CTV. The computed mean translational difference was 1.65, 1.60, and 1.80 mm and the computed mean rotational difference was 1.51°, 3.93°, and 2.09° in the superior/inferior, anterior/posterior, and medial/lateral direction, respectively. The sensitivity of overlap was 87%. The results demonstrate that the automatic registration approach performs registrations comparable to the manual registration.PACS number(s): 87.57.nj, 87.61.‐c, 87.57.Q‐, 87.56.J‐

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“…15 Rectal contrast use is not standardised and Roach et al 16 suggests a nearly empty rectum with 15 cc of contrast to avoid changes in rectal volumes and prostate position. One study 17 examined the variability in prostate contouring on CT versus 1 mm anatomical photographs. An intra-observer variation of 2-8% SD and 18?8% was found among observers in relation to prostate volumes.…”

Section: Rectal Contrastmentioning

confidence: 99%

Dosimetric effects of bladder and rectal contrast agents in prostate radiotherapy

Gleeson

2013

J Radiother Pract

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Background and purpose: Accurate delineation of the target volume and organs at risk (OARs) are vital to ensure systematic errors are small. The use of contrast agents (CAs) in the bladder and rectum may aid contouring and reduce inter and intra-observer variability. The aim of this study was to evaluate the dosimetric effect of the presence of such contrast on the monitor units (MUs), planning target volume (PTV), rectum and bladder.

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A study of prostate delineation referenced against a gold standard created from the visible human data

Cited by 74 publications

References 25 publications

Quantitative Evaluation of Cone Beam Computed Tomography in Target Volume Definition for Offline Image Guided Radiation Therapy of Prostate Cancer

Quantitative Evaluation of Cone Beam Computed Tomography in Target Volume Definition for Offline Image Guided Radiation Therapy of Prostate Cancer

Comparison of manual and automatic MR‐CT registration for radiotherapy of prostate cancer

Dosimetric effects of bladder and rectal contrast agents in prostate radiotherapy

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