A study of pyridinium-type functional polymers. III. Preparation and characterization of insoluble pyridinium-type polymers

Abstract

The copolymers of 4‐vinylpyridine (4VP), styrene (St) and divinylbenzene (DVB) with varied compositions, P(4VP‐St‐DVB), were synthesized by suspension polymerization using 2,2′‐azobisisobutyronitrile (AIBN) as an initiator. The insoluble (crosslinked) pyridinium‐type polymers in benzyl–pyridinium bromide form, which possess various macromolecular chain compositions, were prepared by the reaction of each P(4VP‐St‐DVB) with benzyl bromide (BzBr), respectively. By using different halohydrocarbon RX in the quaternization of P(4VP‐St‐DVB), the insoluble pyridinium‐type polymers with various pyridinium group structures were obtained. The structures of P(4VP‐St‐DVB) and its quaternized product Q‐P(4VP‐St‐DVB) were identified by FTIR. The 4VP content in each copolymer P(4VP‐St‐DVB) was measured by nonaqueous titration; and the pyridinium group content (Cq) in each Q‐P(4VP‐St‐DVB) sample was determined by means of the back titration manner in argentometry and/or the elemental analysis method, respectively. In addition, the particle structure and the surface morphology of the thus‐prepared polymer were observed using SEM. According to a series of experimental results, the preparation and characterization of insoluble pyridinium‐type polymers are analyzed and discussed. This work can prepare the ground for a study on the antibacterial activity of insoluble pyridinium‐type polymers. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 78: 668–675, 2000

Quaternary Ammonium Polyethyleneimine: Antibacterial Activity

“…A number of polycations possessing antimicrobial properties were developed for this purpose including ion exchange fibers [8], alkoxysilanes [9], soluble and insoluble pyridinium-type polymers [10,11], polyionenes [12], polymer surfaces derivatized with poly(vinyl-N-pyridinium) [13,14], and immobilized N-alkylated polyethyleneimine [15][16][17].…”

Contribution of “click chemistry” to the synthesis of antimicrobial aliphatic copolyester

“…The permanency of the effect depends of course on the stability of the bonding between the biocide and the polymer. Typical examples are polymers substituted by quaternary ammonium salts [12][13][14][15], phosphonium salts [16][17][18] and pyridinium cations [19,20]. As a rule, these cationic biocides interact with the negatively charged membrane of the bacteria, which is accordingly disrupted and disintegrated.…”

Polyethyleneimine nanoparticles incorporated into resin composite cause cell death and trigger biofilm stress in vivo

“…Numerous articles have demonstrated the antimicrobial utility of cationic polymers with quaternary ammonium groups (7)(8)(9). In particular, it was reported that quaternary ammonium polyethyleneimine (QPEI) possesses excellent antibacterial activity (10,11).…”