A Study of Some Aspects of Reproduction by Means of Chemical Analysis

Spray, Christine M.

doi:10.1079/bjn19500059

Cited by 102 publications

(22 citation statements)

References 26 publications

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“…On day 21 of gestation, adipose tissue lipogenesis sharply declines [7] which together with an enhanced lipolytic activity [27,28] and a decreased hydrolysis and uptake of circulating triglycerides resulting from a decreased lipoprotein lipase activity [28][29][30] reflects the decline in adipose tissue mass seen in the rat around parturition. This change does not cause a signifi-cant decline in maternal body weight during lactation, probably as a result of the enhanced mammary gland weight [5,31] as well as the high body water content [32] known to occur during this phase. Late pregnancy is characterized by high plasma insulin levels and insulin resistance [8,33,34].…”

Section: Discussionmentioning

confidence: 99%

Plasma Leptin Levels in Rat Mother and Offspring during Pregnancy and Lactation

et al. 2000

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The profiles of plasma leptin levels in pregnant and lactating rats and their offspring were determined. The plasma leptin levels increased on days 12 and 20 of gestation and declined on day 21 of gestation, remaining at this level during lactation. These changes were similar for lumbar adipose tissue weight, and a significant correlation was found when both variables were plotted with individual values. During the last 2 days of intrauterine life, the plasma leptin levels in the fetuses were in the same range as in their mothers, declining from day 20 to day 21. On the 1st day of life, the leptin levels increased to decline in suckling newborns after 4 days, remaining stable until day 20 of life. The enhancement in maternal white adipose tissue mass that takes place during pregnancy and its decline around parturition and lactation are proposed to contribute actively to the changes in the plasma leptin profile detected at these stages. Besides the contribution of placental leptin for the fetus and milk leptin for the suckling newborn, it is proposed that brown adipose tissue, which is the first form of adipose tissue that appears during development in the rat, is responsible for most of the changes in plasma leptin levels seen around birth, whereas its later decline could be mediated by the hormonal changes occurring after birth.

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Section: Discussionmentioning

confidence: 99%

Plasma Leptin Levels in Rat Mother and Offspring during Pregnancy and Lactation

et al. 2000

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“…Weight gain during pregnancy is ac counted for by several factors such as the product of conception, increase in maternal tissues such as enlarged liver and gastro intestinal tract [12], increased hydration of the lean tissues, plus the fetal weight. A pos itive energy balance is achieved in response to the continuous secretion of progesterone [13], and the fat store is increased as well as protein and minerals [11,12,14].…”

Section: Discussionmentioning

confidence: 99%

Effect of Methylxanthines on Lactational Performance of Rats

Hart

Grimble

1990

Ann Nutr Metab

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Caffeine, theophylline and theobromine are commonly consumed methylxanthines. There are conflicting reports that methylxanthines may adversely affect the outcome of pregnancy. The effects of methylxanthines on lactational performance were investigated by administration of pure alkaloids via drinking water to Wistar albino rats throughout pregnancy and lactation. Litter growth was used as an index of lactational performance in relation to maternal food and fluid intake, changes in weight, and lipid content of the carcass. Caffeine induced increased fluid intake (p < 0.01). While theophylline produced no significant differences in litter growth, maternal weight and carcass fat during pregnancy/lactation compared with controls, caffeine and theobromine significantly enhanced litter growth (p < 0.05 and 0.01, respectively). The enhancement in pup growth did not involve increases in maternal food intake or maternal lipid mobilization.

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“…En dépit des nombreux travaux consacrés aux variations de la composition corporelle de la femelle au cours de la gestation (Spray, 1950 ;Beaton et al, 1954 ; Jacquot, 1961 ;Heap et Lodge, 1967 ;Knopp et al, 1973Knopp et al, et 1975Remesar et al, 1981 ;Aitchison, Clegg et Vernon, 1982 ;Steingrimsdottir, Greenwood et Brasel, 1980 ;Naismith, Richardson et Pritchard, 1982) l'accord n'est pas encore fait sur l'importance et la chronologie de la constitution des réserves tant lipidiques que protéiques effectuées par la gestante.…”

Section: Introductionunclassified

Influence d'un régime hyperlipidique sur la lipogenèse, la mise en réserve et l'utilisation des lipides chez la ratte gestante

Champigny¹,

Hitier²,

Kohl³

et al. 1985

Reprod. Nutr. Dévelop.

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Summary. Effect of an hyperlipidic diet on lipogenesis and on the storage and mobilization of lipids in the pregnant rat.The aim of the present investigation was to determine the amount of fat accumulated and mobilized during pregnancy in rats fed either an hyperglucidic or an hyperlipidic diet.The feeding of an hyperlipidic diet increased the liver lipid content and did not modify the composition of the mammary gland.Fat was deposited till day 19 of pregnancy ; after that date the fat was mobilized. The increase and decrease of fat stores were independent of the diet consumed. Both were correlated with body changes so that the same linear relationship between the lipid content of the carcass and maternal body weight was observed at all stages of pregnancy.Introduction.

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A Study of Some Aspects of Reproduction by Means of Chemical Analysis

Abstract: Long and careful balance experiments on pregnant women have shown that more nitrogen, calcium, phosphorus and magnesium was retained by the mother than was required for the body of her newborn baby and its adncxa

Cited by 102 publications

References 26 publications

Plasma Leptin Levels in Rat Mother and Offspring during Pregnancy and Lactation

Plasma Leptin Levels in Rat Mother and Offspring during Pregnancy and Lactation

Effect of Methylxanthines on Lactational Performance of Rats

Influence d'un régime hyperlipidique sur la lipogenèse, la mise en réserve et l'utilisation des lipides chez la ratte gestante

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