A study of western pharmaceuticals contained within samples of Chinese herbal/patent medicines collected from New York City’s Chinatown

Miller, Gretchen M.; Stripp, Richard

doi:10.1016/j.legalmed.2007.04.001

Cited by 38 publications

(17 citation statements)

References 12 publications

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“…For example, a study by the Taiwanese FDA reported the presence of paracetamol, diclofenac and other conventional drugs in Chinese patented medicines for the treatment of ailments ranging from asthma to pain and arthritis [9,10]. Other ingredients have included promethazine and sildenafil [11]. Thus, if Chan Su is prescribed for arthritic pain, the addition of paracetamol and diclofenac would presumably increase the chance of a therapeutic response.…”

Section: Discussionmentioning

confidence: 99%

Sudden death associated with intravenous injection of toad extract

Kostakis

Byard

2009

Forensic Science International

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Section: Discussionmentioning

confidence: 99%

Sudden death associated with intravenous injection of toad extract

Kostakis

Byard

2009

Forensic Science International

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“…Since the extracts from herbal medicines may be quite dirty, TLC may be a good choice for sample analysis. Miller and Stripp [15] used TLC for the extraction of Chinese herbal medicines collected from New York City ' s Chinatown. To increase the chances of fi nding drugs, they used acidic, basic, and neural extraction for each sample.…”

Section: Role Of the Clinical Laboratory In Identifying Such Adulterantsmentioning

confidence: 99%

“…Even if the known spectrum is not available for a particular compound, the GC -MS spectrum may provide information about the structure of an unknown compound. There are a number of publications that used GC -MS for the detection of adulterants in herbal remedies [4,15,29,34] .…”

Section: Role Of the Clinical Laboratory In Identifying Such Adulterantsmentioning

confidence: 99%

Adulteration of Herbal Remedies with Conventional Drugs: Role of the Clinical Laboratory

Garg

Ferguson

2010

Herbal Supplements

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“…1,10-15 Attia et al, have determined the vardenafil hydrocholorides as pure active ingredients in drugs using the TAI (thermal analysis investigation). 16 …”

Section: Introductionmentioning

confidence: 99%

Spectroscopic and Spectrometric Methods Used for the Screening of Certain Herbal Food Supplements Suspected of Adulteration

Cristina¹,

Popescu²,

Radu³

et al. 2017

Adv Pharm Bull

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Purpose: This study was carried out in order to find a reliable method for the fast detection of adulterated herbal food supplements with sexual enhancement claims. As some herbal products are advertised as "all natural", their "efficiency" is often increased by addition of active pharmaceutical ingredients such as PDE-5 inhibitors, which can be a real health threat for the consumer. Methodes: Adulterants, potentially present in 50 herbal food supplements with sexual improvement claims, were detected using 2 spectroscopic methods - Raman and Fourier Transform Infrared - known for reliability, reproductibility, and an easy sample preparation. GC-MS technique was used to confirm the potential adulterants spectra. Results: About 22% (11 out of 50 samples) of herbal food supplements with sexual enhancement claims analyzed by spectroscopic and spectrometric methods proved to be "enriched" with active pharmaceutical compounds such as: sildenafil and two of its analogues, tadalafil and phenolphthalein. The occurence of phenolphthalein could be the reason for the non-relevant results obtained by FTIR method in some samples. 91% of the adulterated herbal food supplements were originating from China. Conclusion: The results of this screening highlighted the necessity for an accurate analysis of all alleged herbal aphrodisiacs on the Romanian market. This is a first such a screening analysis carried out on herbal food supplements with sexual enhancement claims.

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A study of western pharmaceuticals contained within samples of Chinese herbal/patent medicines collected from New York City’s Chinatown

Cited by 38 publications

References 12 publications

Sudden death associated with intravenous injection of toad extract

Sudden death associated with intravenous injection of toad extract

Adulteration of Herbal Remedies with Conventional Drugs: Role of the Clinical Laboratory

Spectroscopic and Spectrometric Methods Used for the Screening of Certain Herbal Food Supplements Suspected of Adulteration

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