A study on assessment of mass drug administration for elimination of lymphatic filariasis in Datia district, Madhya Pradesh

Abstract

Background: Currently 947 million people globally live in areas having endemic lymphatic filariasis and require preventive chemotherapy to stop the spread of infection. LF is transmitted by many mosquitoes particularly Culex and in some areas by Anopheles and Aedes too. This study was conducted to assess the programme implementation with respect to process and outcome indicators and to assess the reasons for non-compliance among population.Methods: We conducted a cross sectional study in Datia district, Madhya Pradesh during September 2014. We determined the sample size for survey based on standard guidelines for MDA coverage assessment. We identified four separate clusters, each with thirty households, for the survey. We selected three clusters from rural areas and one cluster from urban area to ensure adequate representation. We used stratified sampling technique for selection of three rural clusters.Results: We surveyed 859 study participants of Indergarh block, Datia district, residing in 120 households across four clusters. Among 859 study participants, the eligible population (excluding less than two year child and pregnant females) was 92% (790/859). District health authorities reported coverage of MDA across entire district to be 91%. We determined the distribution rate of DEC across all four clusters to be 84% (±9%). We identified highest drug distribution rate in Uchad (97%; 193/200) and lowest in Bargai (75%; 133/178).Conclusions: Non-compliant individuals are potential reservoir for the parasite which may serve as source of infection and transmission even after the mass drug administration ceases. As the prevalence of lymphatic filariasis continues to decrease with the implementation of control measures, addressing the issue of non-compliance holds primary importance to further substantiate the effect of our efforts.

Mid-term assessment of mass drug administration for elimination of lymphatic filariasis: in Bundelkhand region of Madhya Pradesh

“…12 In a similar study conducted in Madhya Pradesh Amarnath G observed coverage rate of 77.47% and compliance rate of 76.21%. 13 Muralidhar et al in their study found coverage rate 84.6% and compliance rate of 56.5%. 14 Abhay et al in their study revealed the overall coverage rate 79.7% and compliance rate 43.04%.…”

“…11.11% respondents had no faith on the drugs and 10.18% persons did not consumed the tablets due to some other reasons. 13 Karmakar PR observed that 30.57% persons did not consume. The most frequent cause was fear of side effect (36.84%) followed not having any clinical manifestation of filariasis (27.82%).…”

Evaluation of coverage, compliance of mass drug administration and assessment of awareness about lymphatic filariasis in Tikamgarh district of Madhya Pradesh: a cross sectional study

“…Only 17.5% had knowledge about transmission of disease, 46.66% had knowledge about availability of treatment and 55.83% had knowledge about MDA programme. 15 Kulkarni et al in their study found that only 49% of subjects had proper knowledge about the disease. 16…”

“…In various study conducted in different place in India by Anil, Lata et al, Naveenkumar, Kishore, Amarnath, Muralidhar et al and Nirgude et al also found low compliance rate than recommended level. [8][9][10][14][15][16][17] There is gender wise and age group wise differences in compliance rate in present study. A detailed inquiry into the matter might help us determine the cultural and social factors related age and gender which could have played a role in the compliance rate.…”

“…In the present study, the coverage rate was 86.5% which is higher as compared to studies by Biradar, Anil, Amarnath, Abhay and lower as compared to studies by Lata and Naveenkumar. 3,[8][9][10]15,17 Coverage rate was highest (87.7%) in 6-14 years age group and lowest (81.9%) in 2-5 years age group. Gender wise coverage was higher (89.94%) in males compared to females ( Table 2).…”