A Study on Clinicopathological Spectrum of Ovarian Tumours in a Tertiary Care Centre

Abstract

BACKGROUND Ovarian cancer is the 6 th most common cancer in worldwide among female population, whereas in India, it is the third most common cancer among women, 1 in 70 women have their lifetime risk to develop this tumour. Survival rate depends on the stage of diagnosis. Although, geographic and racial differences in the incidence of ovarian tumours are well-recognised information regarding any dissimilarity in clinicopathological behaviour is scarce. In the present study, the clinicopathological features of patients with ovarian tumours are evaluated. MATERIALS AND METHODS In a series of 96 clinically and diagnostically-proved ovarian tumours, case history was taken and clinical examination was done. Surgical staging done according to laparotomy, gross morphology and histopathological study was done. Study Type-Observational study, done in between December 2015-March 2017 in Konaseema Institute of Medical Sciences and RF (Research Foundation). RESULTS Out of 96 cases are studied in Konaseema Institute of Medical Sciences and RF, 59 cases are benign and 32 cases are malignant tumour and 5 cases are borderline malignant potential tumours. Most of the tumour presented within 2 months of onset of symptoms, abdominal distension is commonest presentation in (51% of cases). Almost, 71% of the malignant tumour diagnosed at stage III/IV of the disease. CONCLUSION On histopathological study of these tumours, 73% are surface epithelial tumours. Among surface epithelial tumours, serous tumour is the commonest one. So, early diagnosis and prompt treatment (surgery and chemotherapy) definitely reduce the mortality from ovarian tumour.

A Clinico -Pathological Study of Neoplastic and Non-Neoplastic Ovarian Lesions.

“…Incidence of bilaterality in tumours was 20.93% which compares well with other studies. 8,14,15 Neoplastic lesions (61.25%) were more than nonneoplastic lesions (38.75%). Among non-neoplastic lesions, Follicular cysts (67.7%) constituted the majority followed by corpus luteal cysts and endometriotic cysts Similar findings have been reported in other studies with follicular cysts making up 51-74.6% of non-neoplastic lesions.…”

“…All these compare well with other studies. 17,18,19,16,20 Among germ cell tumours, all represented mature cystic teratoma. Sex cord stromal tumours seen in this study were granulosa cell tumours only.…”

“…These findings are similar to other studies where benign tumours were mostly cystic and malignant tumours predominantly showed solid or variegated appearance. 17,21,18…”

Clinico-pathological study of ovarian tumors at tertiary care hospital, Udaipur

“…Most ovarian tumors cannot be distinguished confidently on the basis of their clinical or gross characteristics alone. 2 Dilemma of differentiating a benign from a malignant tumour always exists by clinical examination. Imaging by USG though helps to locate origin size, consistency of tumour but diagnosis of malignancy in ovarian tumour by USG, CA125, MRI and other method is difficult.…”

“…Thus, they concluded that early diagnosis and prompt treatment can definitely reduce the mortality from ovarian tumour. 2…”