A study on copolymeric hydrogels based on acrylamide-methacrylate and its modified vinyl-amine-containing derivative

Abstract

Acrylamide-co-methyl methylacrylate (AAm-coMMA) copolymeric hydrogels of different ratios were prepared by using chemical and physical crosslinks. The physically crosslinked hydrogels were prepared by solution polymerization using benzoyl peroxide as an initiator, while the chemically crosslinked hydrogels were prepared by using N,N-methylene bisacrylamide (N,N-MBA) as crosslinking agent. This copolymeric hydrogel was further modified by Hofmann degradation to improve its swelling behaviour. 1 H-nuclear magnetic resonance (1 H-NMR), Fourier transform infra-red spectroscopy (FT-IR), differential scanning calorimetry (DSC) and elemental analysis have been used to characterize the copolymeric gel. Elemental analysis has been used to evaluate the copolymer composition. The influence of environmental conditions such as temperature and pH value on the swelling behaviour of these copolymeric gels was investigated. Results showed that the hydrogels exhibited different equilibrium swelling ratios at different pH and temperature of swelling medium. The temperature and pH sensitivities of these gels also depended on the AAm content in the copolymeric hydrogels. These hydrogels exhibited 2135% swelling at 60 • C, which was reversible and very good dimensional stability was mentioned. This was due to hydrolysis of amide groups could be hydrolyzed to form negatively charged carboxylate ion in hydrogels in response to an external pH and temperature variation.

Obtaining swelling hydrogels to improve fertility and the benefit of retaining sandy soils

“…The swelling temperature and pH of these gels depended on the content of acrylamide in the macromelic chain. The gels showed 21-35% swelling at 60°C, which was reversible and very stable [4].…”

Polymeric Hydrogels As Drug Delivery Vehicles

“…Co-polymeric hydrogels are made up of two or more two dissimilar monomers in which at least one hydrophilic component should be present. These hydrogels were pH and temperature-sensitive and characterized for drug delivery application [39].…”

Synthesis of poly(acrylamide-co-methyl methacrylate) chemicaly cross-linked hydrogels for efficient adsorption of red erionyl dye

“…When the temperature was raised to 35 °C to 50 °C the degree of swelling increased from 100 to140%, when the AAm content was raised from 25 to 75%. As the temperature increases, the degree of swelling of the hydrogel increased substantially because the amide group becomes more prone to hydrolysis and conversion to acrylic acid (43,44) at high temperature, enhancing hydrophilicity of the gels and causing the gels to absorb more water. The swelling capacity of the hydrogel remains constant after 50 °C, which may indicate that all the possible amide groups have been hydrolysed (43).…”