A Study on Indirect and Intangible Costs for Patients with Knee Osteoarthritis in Singapore

Xie, Feng; Thumboo, Julian; Fong, Kok‐Yong; Lo, Ngai-Nung; Yeo, Seng-Jin; Yang, Kuang-Ying; Li, Shu Chuen

doi:10.1111/j.1524-4733.2008.00371.x

Cited by 42 publications

(37 citation statements)

References 24 publications

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“…Furthermore, initial bid bias is known as one of the limitations of closed-ended iterative bidding approach. 13 Nevertheless, the influence is not statistically significant in this study as demonstrated by Kruskal-Wallis H test for WTP values among 3 initial bids (P ϭ 0.113 in CP patients and P ϭ 0.606 in GP).…”

Section: Discussionmentioning

confidence: 59%

“…13 In this process, subjects were provided with an initial bid and asked whether they would like to pay this specified amount as monthly payment for moving from participant's current health state to a perfect health state, describing with EQ-5D full health state as "11111." If subjects answered positively (or negatively), then the amount was doubled (or halved) until subjects expressed an unwillingness (or willingness) to pay the amount specified.…”

Section: Willingness To Paymentioning

confidence: 99%

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Willingness to Pay per Quality-Adjusted Life Year: Is One Threshold Enough for Decision-Making?

Zhao

Yue²,

Hua³

et al. 2011

Medical Care

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Preference elicitation methods are acceptable and feasible in the socio-cultural context of an Asian environment and the calculation of WTP/QALY ratio produced meaningful answers. The necessity of considering the QALY type or disease-specific QALY in estimating WTP/QALY ratio was highlighted and 1 to 3 times of gross domestic product/capita recommended by World Health Organization could potentially serve as a benchmark for threshold in this Asian context.

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Section: Discussionmentioning

confidence: 59%

Section: Willingness To Paymentioning

confidence: 99%

Willingness to Pay per Quality-Adjusted Life Year: Is One Threshold Enough for Decision-Making?

Zhao

Yue²,

Hua³

et al. 2011

Medical Care

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“…It was assumed that there was no risk of any kind from the administration of such a product, and the effect would remain while being used. WTP was valued by a closed-ended iterative bidding system [14,26]. Each subject was asked if they would be willing to pay a certain amount of their personal money per month.…”

Section: Methodsmentioning

confidence: 99%

Willingness to pay for a quality-adjusted life year: an evaluation of attitudes towards risk and preferences

Fernández

Polentinos-Castro

Cura-González

et al. 2014

BMC Health Serv Res

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BackgroundThis paper examines the Willingness to Pay (WTP) for a quality-adjusted life year (QALY) expressed by people who attended the healthcare system as well as the association of attitude towards risk and other personal characteristics with their response.MethodsHealth-state preferences, measured by EuroQol (EQ-5D-3L), were combined with WTP for recovering a perfect health state. WTP was assessed using close-ended, iterative bidding, contingent valuation method. Data on demographic and socioeconomic characteristics, as well as usage of health services by the subjects were collected. The attitude towards risk was evaluated by collecting risky behaviors data, by the subject’s self-evaluation, and through lottery games.ResultsSix hundred and sixty two subjects participated and 449 stated a utility inferior to 1. WTP/QALY ratios varied significantly when payments with personal money (mean €10,119; median €673) or through taxes (mean €28,187; median €915) were suggested. Family income, area income, higher education level, greater use of healthcare services, and the number of co-inhabitants were associated with greater WTP/QALY ratios. Age and female gender were associated with lower WTP/QALY ratios. Risk inclination was independently associated with a greater WTP/QALY when “out of pocket” payments were suggested. Clear discrepancies were demonstrated between linearity and neutrality towards risk assumptions and experimental results.ConclusionsWTP/QALY ratios vary noticeably based on demographic and socioeconomic characteristics of the subject, but also on their attitude towards risk. Knowing the expression of preferences by patients from this outcome measurement can be of interest for health service planning.

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“…We excluded non-human and in-vitro studies, case reports, review articles, articles with main focuses on outcome of "knee replacement surgeries", "surgical techniques" and "evaluation or validation of outcome instruments". Of 57 articles retrieved that were from Singapore or Asia, we included six articles [10][11][12][13][14][15] . A further two articles were identified from references of included articles 16,17 and one from the Singapore National Health Survey 18 .…”

Section: Methods and Search Resultsmentioning

confidence: 99%

A Perspective on Osteoarthritis Research in Singapore

Leung

Pua

Thumboo

2013

Proceedings of Singapore Healthcare

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Knee osteoarthritis (OA) is common and is one of the five leading causes of disability in Singapore; it entails significant cost to society. Singapore is one of the faster ageing populations in Asia and obesity is on the rise. The public health consequences of OA, particularly knee OA are therefore expected to rise dramatically. There is thus an urgent need for advancement in research in this area. An accurate estimate of the prevalence of knee OA would improve the understanding of its impact in different sectors of society, and facilitate public health decision-making and resource allocation to address this upcoming challenge in public health. Currently there is no proven drug that slows down the osteoarthritis process and management of knee OA is symptomatic. Identification of genetic, environmental, inflammatory and biomechanical risk factors will help us to understand the pathogenesis and find factors for its prevention. There is a need for early diagnosis of knee OA and identifying subjects who are more likely to benefit from drug treatment. Effort is needed in the discovery of drugs that have disease modifying effect to treat this disabling disease. Understanding the biomechanical factors underlying knee OA may also lead to the discovery of new recommendation and treatment strategies.

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A Study on Indirect and Intangible Costs for Patients with Knee Osteoarthritis in Singapore

Abstract: This study demonstrated that eliciting indirect costs through human capital approach and intangible costs through WTP are acceptable and feasible in Asian patients with knee OA. Besides the direct costs, the indirect and intangible costs for the OA patients could be substantial.

Cited by 42 publications

References 24 publications

Willingness to Pay per Quality-Adjusted Life Year: Is One Threshold Enough for Decision-Making?

Willingness to Pay per Quality-Adjusted Life Year: Is One Threshold Enough for Decision-Making?

Willingness to pay for a quality-adjusted life year: an evaluation of attitudes towards risk and preferences

A Perspective on Osteoarthritis Research in Singapore

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