Biodegradable materials suitable for medical application with improved corrosion resistance and good biocompatibility along with enhanced mechanical properties are the need of the hour. Such properties in Mg-Zn-Ca glass forming alloy used as a metal matrix can be obtained through proper reinforcement. Hydroxyapatite (HA) which is a mineral constituent of natural bone has a wide range of medical applications because of its excellent biocompatibility and bioactivity. They promote bone cell adhesion and osteoblastic proliferation. In the present study, the influence of HA particle (HA p ) addition on the glass forming ability, corrosion resistance, mechanical behavior and cytocompatibility of Mg 66 Zn 30 Ca 4 alloy has been investigated. The addition of HA p decreases the glass forming ability of Mg 66 Zn 30 Ca 4 alloy. Significant improvement in corrosion resistance along with marginal improvement in mechanical properties is observed upon addition of HA p . Moreover, HA p incorporation into Mg 66 Zn 30 Ca 4 metallic glass has enhanced the cell viability and cell adhesion of human osteoblast-like cell (MG63) cells, complementing the excellent biocompatibility, bioactivity, osteoconductivity and osteoinductivity of hydroxyapatite mineral due to its biomimetic nature. HA reinforcement is not only a promising approach to improve the corrosion resistance, but also offers a biomimitic interface to enhance osseointegration and overall competence of orthopedic implants.