A Study on Phytochemical Analysis of Phyllanthus Tenellus Roxb.

Komuraiah, Ananthagiri; Ragan, Ajmeera

doi:10.7897/2230-8407.086104

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…This finding is similar to Igwe et al, [21] who stated that phyllantus plant contain high levels of saponins and tannins with low content of cyanogenic glycosides. P. amarus has also been reported to have high amounts of alkaloids and phenols [22], alkaloids, tannins, and flavonoids [23], flavonoids, tannins, alkaloids, terpenoids, steroids, saponins and cardiac glycosides [24] which are in line with our findings. The presence of these phytochemicals are likely to be behind its pharmacological effects as reported by many authors.…”

Section: Discussionsupporting

confidence: 91%

Determination of Phytochemical Composition and the Effects of Ethanol Extract of Phyllanthus urinaria on the Liver and Kidney Function Parameters in Paracetamol-Administered Albino Rat Models

Enemali,

John,

Abdullahi

et al. 2023

JOCAMR

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The current study was aimed at determining the phytochemical composition and the effects of Phyllantus urinaria Ethanol extract on the liver and kidneys by using albino rats as the animal models. All the analyses were carried out following standard laboratory methods and procedures. A total of fifteen rats were randomly distributed into three groups of five rats in each group where group one served as the control while the test groups comprise of 1000mg/kg body weight (b.w) and 500mg/kg b.w administered daily for fourteen days and followed by administration of a high dose of paracetamol (200mg/kg b.w) to challenge the system toxicologically. This was deliberately done to note whether the extract having administered for many days will protect the liver and kidneys against the paracetamol by determining the serum biomarkers. The results showed the presence of saponins (8.84 g/100g), tannins (1.32 g/100g), phenols (0.11 g/100g), flavonoids (0.512 g/100g) and alkaloids (0.038 g/100g) while cardiac glycosides, Resins, terpenoids and steroids were not detected. The activity of ALP was significantly (p < 0.05) higher in both the 1000mg/kg b.w and 500mg/kg b.w. There was no significant (p>0.05) decrease in ALT activity of 1000mg/kg b.w and at 500mg/kg b.w. the activity of ALT significant (p>0.05) increased when compared with the control. There was a significant (p<0.05) decrease in AST activity of 1000mg/kg b.w and 500mg/kg b.w when compared with the control. Bilirubin concentration significantly (p< 0.05) decreased at 1000mg/kg b.w and non-significantly (p>0.05) increased at 500mg/kg b.w. ALB significantly (p > 0.05) increased at 1000mg/kg b.w and 500mg/kg b.w. A non-significant decrease in Serum HCO3- in both 1000mg/kg/b.w and 500mg/kg b.w. Urea non-significantly decreased at both 1000mg/kg b.w and 500mg/kg b.w. Creatinine significantly increased at both 1000mg/kg b.w and 500mg/kg b.w concentration when compared to the control. Na+ showed a non-significant increase at 1000mg/kg b.w and 500mg/kg b.w when compared to the control. The extract may not have protected the liver and kidneys against paracetamol despite the presence of some phytochemicals, a histological examination of the liver and kidneys is therefore recommended so as to have a clearer picture of the effects observed.

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Section: Discussionsupporting

confidence: 91%

Determination of Phytochemical Composition and the Effects of Ethanol Extract of Phyllanthus urinaria on the Liver and Kidney Function Parameters in Paracetamol-Administered Albino Rat Models

Enemali,

John,

Abdullahi

et al. 2023

JOCAMR

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“…The highest total tannin levels (another phenolic compound group) from the P. tenellus extract could be a response to the stressful environment in which this invasive species was collected 33 , area with stones, few soil and water deficit, in the microregion of Campina Grande, Paraíba, Brazil, with few soil and water deficits. The tannin accumulation, in this case, has an antioxidative function 34 www.nature.com/scientificreports www.nature.com/scientificreports/ (80%) of the whole P. tenellus plant 35 . The highest phenolic compound content and total carotenoids in the C. papaya L. seed extract is due to its function in sanity and resistance to pests and diseases, as a strategy for seed survival 36 , mainly against oxidative stress 37 .…”

Section: Discussionmentioning

confidence: 99%

Green leaves and seeds alcoholic extract controls Sporobulus indicus germination in laboratory conditions

Macêdo

Ribeiro

Bruno

et al. 2020

Sci Rep

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High seed production makes Sporobolus indicus var. pyramidalis a difficult to control invasive grassland plant. The objective of the present study was to investigate the bioactivity of Cyperus rotundus, Phyllanthus tenellus and Ricinus communis green leaf extracts and of Carica papaya seeds on S. indicus germination without breaking dormancy, simulating the field conditions. The ethanolic extract bioactivity of C. rotundus, P. tenellus, R. communis green leaves and C. papaya seeds, at concentrations of 25, 50 and 75% in S. indicus germination was evaluated. Carotenoids, flavonoids, soluble phenolic compounds and total tannins were quantified in the extracts. The chemical component concentrations varied between alcoholic extracts. The P. tenellus extracts at all dilutions and those of R. communis and C. papaya at 75% completely suppressed S. indicus seed germination at five and ten days which can be attributed to their high tannin concentration, total phenolic compounds and flavonoids.

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“…Solutions were made with dry plant extracts dissolved in DMSO and applied to agar plates. Zones of inhibition were measured after incubation [20][21][22].…”

Section: Antimicrobial Activities (Disk Diffusion Method)mentioning

confidence: 99%

The bio-constituents extracted from Silybum marianum L plant and its effects as antimicrobial

Melad,

Alsadi,

Edrah

2023

JPAM

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A Study on Phytochemical Analysis of Phyllanthus Tenellus Roxb.

Cited by 3 publications

References 12 publications

Determination of Phytochemical Composition and the Effects of Ethanol Extract of Phyllanthus urinaria on the Liver and Kidney Function Parameters in Paracetamol-Administered Albino Rat Models

Determination of Phytochemical Composition and the Effects of Ethanol Extract of Phyllanthus urinaria on the Liver and Kidney Function Parameters in Paracetamol-Administered Albino Rat Models

Green leaves and seeds alcoholic extract controls Sporobulus indicus germination in laboratory conditions

The bio-constituents extracted from Silybum marianum L plant and its effects as antimicrobial

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