The knowledge of human body proportions and segmental properties of limbs, head and trunk is of fundamental importance in biomechanical research. Given that many methods are employed, it is important to know which ones are currently available, which data on human body masses, lengths, center of mass (COM) location, weights and moment of inertia (MOI) are available and which methods are most suitable for specific research purposes. Graphical, optical, x-ray and derived techniques, MRI, laser, thermography, has been employed for in-vivo measurement, while direct measurements involve cadaveric studies with dissection and various methods of acquiring shape and size of body segments. The present review examines the literature concerning human body segments’ properties for biomechanical purposes starting with a historical examination. It emerges that data obtained in studies on cadaveric specimens are still accurate in comparison to more recent technologies, whilst technological tools currently available are manifolds, each one with proper advantages and disadvantages. Classical studies were focused mainly on white men, while in recent years, the available data on body segments have been extended to children, women, and other races. Additionally, data on special populations (obese, pregnant women) are starting to appear in the scientific literature.