In this study, the self-esteem by grasping the adaptation state of the stress and school multi-cultural youth, social support, and analyzed the changes that appear in response to them coping with stress. By utilizing the structural equations for that, this study analyzed the relationship between the adaptation to stress and school multi-cultural youth, in terms of coping with stress, social support, and examined the effect of adjusting the self-esteem of the parameters. The results of this study were as follows. Stress multi-cultural youth, social support and self-esteem are affected. On the other hand, a significant effect on coping with stress was not detected. Subsequently, to cope with the stress analyzed, social support, self-esteem effects of the defined parameters revealed a relationship between the adaptation to all stresses and school life.