The installation of successional heating devices in industrial buildings will result in thermal corridors. To improve the thermal environment in and around these corridors, buoyancy-driven ventilation is commonly utilized to dissipate heat, which is based on the natural convection design for buildings. However, the flow and heat exchange patterns of natural convection related to thermal corridors have not been clearly clarified, and no relevant correlations have been established to quantify them. The conducted numerical study aimed to analyze the flow and heat transfer characteristics of natural convection within thermal corridors in industrial buildings. Experimental data were utilized to validate a computational fluid dynamics (CFD) model developed for this purpose. The study considered the influence of various parameters on the results obtained. In the side corridor, the prevalence of reverse flow dominates much of the channel, while in the middle corridor, reverse flow near the bottom corner is observed. The ambient air temperature significantly impacts the temperature distribution in both corridors. Increasing the ambient air temperature at the inlet from 22 to 28 °C results in a substantial temperature rise within the corridor, by approximately 6–7 °C. When the outlet size is constant and the inlet size drops by 30%, the air temperature in the corridor increases by 3 °C. Finally, correlations were established based on the simulation data to predict the surface-averaged Nu¯ of the heated wall and the induced mass flow rate, m˙, of the natural convection. The correlations have relative errors of less than 16% when compared to the simulation data.