Novel cadmium-doped Bi 2 WO 6 nanoparticles with different Cd contents have been synthesized by a one-step route using ethylene glycol and water as solvents at 180°C for 12 h. The as-synthesized samples were characterized in detailed by SEM, XRD, EDS, HRTEM, UV-Vis DRS, BET techniques, and so on. The results shown that with the increase of the Cd 2? addition, the crystal structure, lattice space, and absorption edge were not significantly changed and the calculated band gap value was 2.58 eV. However, the flower-like Bi 2 WO 6 sphere was gradually destroyed. Simultaneously, the surface area and photocurrent responses of the catalysts were greatly increased. Photocatalytic activity of the Cd-doped Bi 2 WO 6 samples was determined by monitoring the change of RhB concentration under simulated solar light. The results revealed that cadmium doping greatly improved the photocatalytic efficiency of Bi 2 WO 6 . The Bi 2 WO 6 sample with R Cd = 0.05 displayed the highest photocatalytic activity, and the degradation rate is about two times greater than pure Bi 2 WO 6 . Moreover, the Cd-Bi 2 WO 6 photocatalyst remained stable even after five consecutive cycles. A possible mechanism of photocatalytic activity enhancement on basis of the experimental results was proposed.