A Survey of Epithelial Odontogenic Tumors and Cysts in Dogs and Cats

Abstract

Abstract.A retrospective histologic study of 12 canine and eight feline epithelial odontogenic tumors and cysts was conducted from oral masses (n = 3,9 17) obtained between 1980 and 1990. No sex or breed predilection was identified. Ameloblastoma was observed in two dogs (case Nos. 1, 2) 6 and 8 months of age. Calcifying epithelial odontogenic tumors were seen in a dog (case No. 3) and in two cats (case Nos. 4, 5) between 8 and 16 years of age. Ameloblastic fibroma (or fibroameloblastoma) was observed in cats (case Nos. 6-10) only. Inductive fibroameloblastoma was observed in four cats (case Nos. 6-9) up to 1 year of age, whereas ameloblastic fibroma was seen in a 14-year-old cat (case No. 10). A single ameloblastic odontoma was identified in a 20-month-old dog (case No. 11). Two complex odontomas occurred in a 6-month-old (case No. 12) and a 4-yearold (case No. 13) dog. Odontogenic cysts were identified in five dogs (case Nos. 14-1 8) aged 4.5 months to 16 years and in a 1 -year-old cat (case No. 19) and have not been previously reported in these species. These cysts were lined by a stratified epithelium reminiscent of the appearance of ameloblastic epithelium. An odontogenic keratocyst with prominent central parakeratotic keratinization was identified in one 9-year-old female dog (case No. 20). Almost all epithelial odontogenic tumors were circumscribed, benign tumors that warranted a good prognosis for survival, although local recurrence may have followed (or may follow) incomplete excision. Calcifying epithelial odontogenic tumors may be locally invasive. Of six odontogenic cysts (case Nos. 14-1 9), two (case Nos. 15, 18) gave rise to basi-squamous carcinomas. The classification and behavior of epithelial odontogenic tumors and cysts in human beings, dogs, and cats are discussed.

Amyloid-Producing Odontogenic Tumor in a Shih-Tzu Dog.

“…Four canine and 8 feline cases of CEOT have been reported in foreign countries [1,[4][5][6][7][8]. The canine cases were more than 8 years old, but the present case was 9 months of age.…”

“…Calcifying epithelial odontogenic tumor (CEOT) is rare in animals and characterized by epithelial proliferation, mineralization in the epithelium and stroma, and deposition of amyloid or amyloid-like materials [1,[4][5][6][7][8]. This note is to report histopathology and immunohistochemistry of CEOT in a Shih-Tzu dog.…”

Peripheral Acanthomatous Ameloblasoma in a Rabbit with Review of Previous Submissions of the Armed Forces Institute of Pathology Wednesday Slide Conference

“…Odontogenic tumors, including epithelial odontogenic tumors are rare in animals [5,[8][9][10]12]. Only two reference cases of ameloblasoma in rabbits have been submitted to the Armed Forces Institute of Pathology Wednesday Slide Conference, Case I-388 (AFIP 2578783) and Case II-97N172 (AFIP 2638859).…”

“…The main subtypes are follicular, plexiform, acanthomatous, basal cell, and granular cell types [6,10]. Follicular ameloblastomas typically consist of epithelial islands with a peripheral palisaded cell layer surrounding a central stellate reticulum area, whereas the tumour epithelium in the plexiform type is arranged in irregular masses or anastomosing cords.…”

Extensive Bilateral Odontogenic Cysts in the Mandible of a Dog

“…1 Types of odontogenic cysts reported in dogs include radicular cysts, dentigerous cysts, and keratocysts. 2,4,8,10,12 In contrast to other odontogenic cysts, radicular cysts are associated with an inflammatory infiltrate. 6 They are also very often found in association with a devitalized tooth.…”