A survey of pre-school children who are often ill and the ways of their improvement

Abstract

The study involved 38 children of sickly, acute respiratory infections with functional bowel disorders, also 35 children occasionally ill (the comparison group) and 20 sickly children (the control group) of the same age, the same epidemic season. All of the children were visited by organized groups. Clinical, immunological and microbiological features of the pre-school children were studied. The efficiency of the use of complex preparations Cycloferon tablets and probiotic drag Biovestin-lacto was evaluated. The disorders of the quantitative and qualitative composition of the microflora were found. The state of cellular and humoral immunity revealed pathology of all its units. The study of antibodies in saliva and coprofilia had deviation from the norm. The use of complex preparations had a favorable impact, namely: the number of violations significant degrees in cellular and humoral links of immunity in sickly children with intestinal dysbiosis decreased in 1,5-2 times; protective properties of local immunity of the mucous membranes increased; violated the large intestine microbiocenosis restored. The complex preparations has expressed prophylactic activity, which is manifested by the reduction in the incidence of acute respiratory infections in 2 times, complications 1.5 times, as well as the severity of the disease.