A Survey of the Plants of Bhagalpur and Santhal Pargana for Saponin, Flavonoids and Alkaloids

Sinha, S. P.; Dogra, J. V. V.

doi:10.3109/13880208509069006

Cited by 31 publications

(7 citation statements)

References 3 publications

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“…The phytochemical composition of A. conyzoides appears to be like that of M. villosus [18]. These results are similar to those found by other researchers for the leaves of A. conyzoides [33,34] and N. laevis [35][36][37].…”

Section: Phytochemical Groupssupporting

confidence: 88%

Antifungal Activity on the Strain of Lasiodiplodia theobromae and Phytochemical Study of Ageratum conyzoides and Newbouldia laevis from the Kisangani Region / DR Congo

Kwembe

Mbula

Onautshu

et al. 2020

IJPR

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Aims: To extract, identify and evaluate in vitro the antifungal activity of the phytochemical groups of Ageratum conyzoides and Newbouldia laevis on the strain of Lasiodiplodia theobromae. Study Design: Exploitation of medicinal plants to combat the growth of L. theobromae, responsible for the decline of cocoa cultivation. Location and Duration of Studies: Faculty of Sciences, University of Kisangani, between April 2017 and February 2018. Methodology: The crude extracts of the dry leaves of A. conyzoides and N. laevis were tested (at 100 mg/mL). Potato dextrose agar was used as the culture medium. After chemical screening, abundant phytochemical groups were isolated and tested. Results: The aqueous, 95% ethanolic and ethereal crude extracts of A. conyzoides are more antifungal (respective percentages of inhibition PI: 80.74; 84.10 and 85.64%) than those of N. laevis (63.28; 72.64 and 75.23%). The minimum inhibitory concentration (MIC) of the aqueous crude extract of A. conyzoides is lower (25 mg/mL) than that of the ethanolic extract (50 mg/mL). Tannins are very abundant in A. conyzoides and in N. laevis. Saponins, sterols and terpenes are abundant in both plants. The extraction yields of tannins and saponins are respectively 20.67 and 2.43% in A. conyzoides and 10.47 and 2.38% in N. laevis. A. conyzoides contains the gallic tannins while N. laevis, the condensates and catechics. The saponins and tannins of A. conyzoides are more antifungal (respective PI: 84.40 and 54.44%) than those of N. laevis (PI: 75.56 and 32.96%). Discussion: The saponins of A. conyzoides and N. laevis are more active on the strain of L. theobromae than the tannins. Saponins are surfactants that can destabilize membrane structure of microorganisms including fungi. Conclusion: The saponins of the two plants have shown a very interesting antifungal power on the strain of L. theobromae. The identification of their active molecules is ongoing.

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Section: Phytochemical Groupssupporting

confidence: 88%

Antifungal Activity on the Strain of Lasiodiplodia theobromae and Phytochemical Study of Ageratum conyzoides and Newbouldia laevis from the Kisangani Region / DR Congo

Kwembe

Mbula

Onautshu

et al. 2020

IJPR

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“…Previous phytochemical investigations (Sinha & Dogra, 1985) showed it to contain saponins, flavonoids, al-…”

Section: Introductionmentioning

confidence: 99%

Biological Activity of Extracts in Relationship to Structure of Pure Isolates ofAbutilon indicum

Yasmin

Kashmiri

Ahmad

et al. 2008

Pharmaceutical Biology

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The present investigations were undertaken to determine the antibacterial and antifungal activity of the crude extract (CE) of plant parts of Abutilon indicum L. (Malvaceae) in relation to the structure of all previous isolates active and inactive against three Gram-negative bacteria, four Gram-positive rods, and three fungi using agar diffusion method. The results suggested some importance and influence of the hydroxyl groups in the isolates structures such as steroids, flavonoids, glycerides, and coumarins on the activity. The material tested had exhibited excellent activity compared to some of the typical antibiotics against both Gram-positive and Gram-negative bacteria. In summary the results obtained with this plant extract may be considered very promising, indicating the potential for obtaining new antimicrobial agents.

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“…(Pedaliaceae) is a wild herb growing in tropical Africa which has several uses in African traditional medicine. The roots are employed to hasten delivery of babies, the stems for their antihemorrhagic and painkilling properties after tooth removal, and the leaves are utilized to cure smallpox and as a soap substitute [l].Previous phytochemical studies on the genus Sesamum have been almost exclusively confined to Sesamum indicum L. A flavonoid [2] and several lignans [3] [4] have been isolated from this species; phenolic acids have been identified [5] [6], and the presence of saponins and alkaloids has also been reported [7] [8]. Very little is known about the constituents of S. angolense.…”

mentioning

confidence: 99%

“…Previous phytochemical studies on the genus Sesamum have been almost exclusively confined to Sesamum indicum L. A flavonoid [2] and several lignans [3] [4] have been isolated from this species; phenolic acids have been identified [5] [6], and the presence of saponins and alkaloids has also been reported [7] [8]. Very little is known about the constituents of S. angolense.…”

mentioning

confidence: 99%

ChemInform Abstract: Two New Antifungal Naphthoxirene Derivatives and Their Glucosides from Sesamum angolense Welw.

et al. 1987

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Two novel naphthoxirene derivatives 1 and 2 and their glucosides 3 and 4 have been isolated from the root bark of Sesarnurn angolense WELW. (Pedaliaceae) by preparative liquid chromatography. The structure of 1 was established by X-ray diffraction analysis. The identities of the other naphthoxirenes were deduced by spectroscopic (IR, UV, 'H-NMR, I3C-NMR, EI-MS, DCI-MS) and chemical methods (oxidation, acid and enzymatic hydrolysis). Compounds 1-3 exhibited antifungal activity. Naphthoxirene 1 was, in addition, cytotoxic to human colon carcinoma cells. During preliminary screening, the CH,Cl, extract of the root bark of S. angolense exhibited antifungal activity against Cladosporium cucumerinum, a plant pathogenic fungus, as well as cytotoxicity towards human colon cancer cells.Here, we report the isolation and structure elucidation of the antifungal constituents from the root bark which were shown to be new naphthoxirene derivatives. One of them also possessed cytotoxic properties and was responsible for the antiproliferative activity of the CH,Cl, extract.

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A Survey of the Plants of Bhagalpur and Santhal Pargana for Saponin, Flavonoids and Alkaloids

Cited by 31 publications

References 3 publications

Antifungal Activity on the Strain of Lasiodiplodia theobromae and Phytochemical Study of Ageratum conyzoides and Newbouldia laevis from the Kisangani Region / DR Congo

Antifungal Activity on the Strain of Lasiodiplodia theobromae and Phytochemical Study of Ageratum conyzoides and Newbouldia laevis from the Kisangani Region / DR Congo

Biological Activity of Extracts in Relationship to Structure of Pure Isolates ofAbutilon indicum

ChemInform Abstract: Two New Antifungal Naphthoxirene Derivatives and Their Glucosides from Sesamum angolense Welw.

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