COVID 19 is a global threat and globally spreading. The international cooperation involving indigenous
peoples and local communities is urgently required in joint prevention to control the epidemic.
Currently, many indigenous populations are continuing to face COVID 19. This study is concerned about
the dynamic of COVID 19 pandemic among indigenous populations living in the remote Amazon
rainforest enclaves. Using the Susceptible Infectious Recovered (SIR) model, the spread of the COVID 19
under 3 intervention scenarios (low, moderate, high) is simulated and predicted in indigenous tribe
populations. The SIR model forecasts that without intervention, the epidemic peak may reach within 10
20 days. Nonetheless the peak can be reduced with strict interventions. Under low intervention, the
COVID 19 cases are reduced to 73% and 56% of the total populations. While, in the scenario of high
intervention, the COVID 19 peaks can be reduced to values ranging from 53% to 15% .To conclude, the
simulated interventions tested by SIR model have reduced the pandemic peak and flattened the COVID
19 curve in indigenous populations. Nonetheless, it is mandatory to strengthen all mitigation efforts,
reduce exposures, and decrease transmission rate as possible for COVID 19 containment.