A symptom questionnaire for hypertensive patients

Bulpitt, Christopher J.; Dollery, C. T.; Carne, Stuart

doi:10.1016/0021-9681(74)90094-0

Cited by 97 publications

(34 citation statements)

References 7 publications

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“…One interpretation is that the sideeffects of 13-adrenoceptor blockers may affect the quality of life. However, the comparison was with non-hypertensive subjects, and it has been shown that hypertension itself (or the effect of labelling) may cause symptoms in the absence of drug treatment (Bulpitt et al, 1974). These results confirm that VAS are able to detect certain side-effects among hypertensive patients taking 1-adrenoceptor blockers.…”

Section: Discussionsupporting

confidence: 75%

Side‐effects of beta‐adrenoceptor blocking drugs assessed by visual analogue scales.

Lewis¹,

Jackson²,

Ramsay³

1985

Brit J Clinical Pharma

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A series of visual analogue scales (VAS) was used to examine the prevalence of side‐effects among hypertensive patients taking beta‐ adrenoceptor blocking drugs. When compared to untreated non‐ hypertensive control subjects, patients taking beta‐adrenoceptor blockers had a greater prevalence of tired legs (P less than 0.001), cold digits (P less than 0.01), insomnia (P less than 0.01) and loss of overall wellbeing (P less than 0.01). Side‐effects did not differ significantly between patients taking atenolol (n = 30), oxprenolol (n = 16), propranolol (n = 15) or metoprolol (n = 10). If there is an important difference in the prevalence of side‐effects between different beta‐adrenoceptor blockers, a much larger study will be needed to demonstrate it.

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Section: Discussionsupporting

confidence: 75%

Side‐effects of beta‐adrenoceptor blocking drugs assessed by visual analogue scales.

Lewis¹,

Jackson²,

Ramsay³

1985

Brit J Clinical Pharma

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“…However, Bulpitt et al 34 reported that 17% of untreated hypertensives had ED while only 7% of normotensive men of comparable age were affected. In a group of 472 men being evaluated for ED, 117 (24.8%) had hypertension.…”

Section: Discussionmentioning

confidence: 99%

Erectile dysfunction in general medicine practice: prevalence and clinical correlates

et al. 2000

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Erectile dysfunction (ED) is a common problem in general medical practice affecting especially the elderly and those with cardiovascular disease and diabetes mellitus. A study was undertaken by questionnaire distributed to consecutive adult male attendees at 62 general medical practices. 1240 completed questionnaires were available for analysis. The mean age of participants was 56.4 y (range 18 ± 91 y). 488 men (39.4%) reported ED: 119 (9.6%)`occasionally', 110 (8.9%)`often', and 231 (18.6%)`all the time' (complete ED). Among 707 men aged 40±69 y 240 (33.9%) reported ED and 84 (11.9%) had complete ED. The prevalence of complete ED increased with age, rising from 2.0% in the 40 ± 49 y age group to 44.9% in the 70±79 y age group. Only 11.6% of men with ED had received treatment. Hypertension, ischaemic heart disease, peripheral vascular disease and diabetes mellitus were frequently associated with ED. 40% of diabetic men aged 60 y or older had ED all the time.

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“…2,24,[29][30][31][32][43][44][45] Hypertension and vascular disease have been reported to be risk factors for ED. 2,27,28,44,[46][47][48][49] In addition, the prevalence of ED is reported to be higher in men taking certain medications, including hypoglycemic agents, antihypertensive or cardiac drugs, diuretics and antidepressants. 2,[50][51][52][53] We also observed a higher prevalence of ED in patients who had hypertension or cardiovascular disease.…”

Section: Ed Diabetes and Viagra G Yang Et Almentioning

confidence: 99%

Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus

Yang

Chen

2010

Int J Impot Res

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The aims of this study were to investigate the prevalence of ED in Chinese men with type 2 diabetes mellitus, and evaluate the efficacy and safety of sildenafil citrate in these patients. Patients from 42 outpatient diabetes clinics with type 2 diabetes mellitus and ED as defined by the International Index of Erectile Function (IIEF)-5 were studied. Participants with ED received three doses (100 mg each) of sildenafil citrate for use over 3 months. Efficacy of sildenafil citrate was assessed using the IIEF-5 and the Global Efficacy Questionnaire (GEQ). Adverse events were recorded by patients in a daily diary. A total of 5477 participants were evaluated, and 75.2% had ED. Age, duration of diabetes and glycosylated hemoglobin (HbA 1 c) 46.5% were independently and significantly associated with the presence and degree of ED. Patients who received pharmacotherapy (N ¼ 389) reported significant improvements. The rate of erections as determined by the GEQ was also significantly improved following treatment. ED is a common complication in Chinese men with type 2 diabetes mellitus, and certain risk factors are associated with the presence of ED and severity. Sildenafil citrate is a safe and effective treatment for these patients.

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A symptom questionnaire for hypertensive patients

Cited by 97 publications

References 7 publications

Side‐effects of beta‐adrenoceptor blocking drugs assessed by visual analogue scales.

Side‐effects of beta‐adrenoceptor blocking drugs assessed by visual analogue scales.

Erectile dysfunction in general medicine practice: prevalence and clinical correlates

Prevalence of erectile dysfunction among Chinese men with type 2 diabetes mellitus

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