A System-on-Chip Digital pH Meter for Use in a Wireless Diagnostic Capsule

Abstract

Abstract-This paper describes the design and implementation of a system-on-chip digital pH meter, for use in a wireless capsule application. The system is organized around an 8-bit microcontroller, designed to be functionally identical to the Motorola 6805. The analog subsystem contains a floating-electrode ISFET, which is fully compatible with a commercial CMOS process. On-chip programmable voltage references and multiplexors permit flexibility with the minimum of external connections. The chip is designed in a modular fashion to facilitate verification and component re-use. The single-chip pH meter can be directly connected to a personal computer, and gives a response of 37 bits/pH, within an operating range of 7 pH units.

A fully integrated wireless SoC for in-body pH and temperature continuous monitoring

“…As for GERD, the traditional method is gastroscopy, which brings great pain to patients and fails to record the physiological parameters such as pH and temperature for a long time. To solve these problems, a smart capsule [1]- [2] with sensors and data processing system on chip (SoC) was proposed. However, these works didn't give out a fully integrated solution or the prototype of the whole system.…”

An implantable ZigBee ready telemetric platform for in vivo monitoring of physiological parameters

“…Percutaneous connections with leads and cables present obvious disadvantages: they limit the patient's mobility and, moreover, they can cause skin irritations or infections, thus contributing to deteriorate health conditions. Although a wireless link is not an essential requirement for physiological parameters monitoring from implanted sensors, the aforementioned issue is one of the main motivations for the trend in Other systems aimed at monitoring pH consist of sensors placed inside a swallowable capsule that can transmit the acquired signal while traveling through the gastro-intestinal tract [9,10].…”

Polarization analyzing CMOS sensor for microchamber/microfluidic system based on image sensor technology

“…Sensing functions expected for such CMOS sensor include light [1][2][3], temperature, pH [4][5][6], and electrochemical sensing [3,7]. Especially, we are interested in optical polarization analysis, because it enables to analyze the chirality of reactants.…”