A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

Nazer, Lama; López-Olivo, María A.; Brown, Anne Rain; Cuenca, John; Sirimaturos, Michael; Habash, Khader; Al-Qadheeb, Nada S.; May, Heather; Milano, Victoria; Taylor, Amy; Nates, Joseph L.

doi:10.1097/cce.0000000000000757

Cited by 8 publications

(5 citation statements)

References 70 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2 Aunque el diagnóstico más temprano, la introducción de nuevos tratamientos para el cáncer y los avances en cuidados intensivos han mejorado el pronóstico de los pacientes que requieren soporte orgánico durante la hospitalización, 3 la mortalidad hospitalaria continúa siendo mayor a 40 %. 4 Para la operación diaria de centros hospitalarios con alto volumen de pacientes o con recursos limitados, es necesario disponer de herramientas o escalas sencillas, de bajo costo y con variables clínicas que se puedan obtener al momento de la exploración física de los enfermos, que permitan identificar a los pacientes con mayor riesgo de muerte durante la hospitalización o en los servicios de urgencias. Ingresar a los pacientes con cáncer a las unidades de cuidados intensivos (UCI) es una decisión compleja y en numerosos centros hospitalarios se considera una medida de baja prioridad en comparación con las necesidades de pacientes con enfermedades no oncológicas.…”

Section: Antecedentesunclassified

Utilidad de la puntuación qSOFA para predecir mortalidad hospitalaria en pacientes con cáncer

Olvera-Alanis,

Óamendys-Silva,

Córdova-Sánchez

et al. 2024

GMM

View full text Add to dashboard Cite

Antecedentes: El quick Sequential Sepsis-related Organ Failure Assessment (qSOFA) es una puntuación propuesta para identificar de forma rápida a pacientes con mayor probabilidad de morir. Objetivo: Describir la utilidad de la puntuación qSOFA para predecir mortalidad hospitalaria en pacientes con cáncer. Material y métodos: Estudio transversal realizado entre enero de 2021 y diciembre de 2022. La mortalidad hospitalaria fue la variable dependiente. Se calculó el área bajo la curva ROC (ABC) para determinar la capacidad discriminativa de qSOFA para predecir mortalidad hospitalaria. Resultados: Se incluyeron 587 pacientes con cáncer. La puntuación qSOFA < 1 obtuvo una sensibilidad de 57.2 %, una especificidad de 78.5 %, un valor predictivo positivo de 55.4 % y un valor predictivo negativo de 79.7 %. El ABC de qSOFA para predecir mortalidad hospitalaria fue de 0.70. La mortalidad hospitalaria de los pacientes con qSOFA de 2 y 3 puntos fue de 52.7 y 64.4 %, respectivamente. La mortalidad hospitalaria fue de 31.9 % (187/587). Conclusión: qSOFA mostró capacidad discriminativa aceptable para predecir mortalidad hospitalaria en pacientes con cáncer.

show abstract

Section: Antecedentesunclassified

Utilidad de la puntuación qSOFA para predecir mortalidad hospitalaria en pacientes con cáncer

Olvera-Alanis,

Óamendys-Silva,

Córdova-Sánchez

et al. 2024

GMM

View full text Add to dashboard Cite

show abstract

“…In a large national cohort study from the Netherlands, the one-year mortality of cancer patients with an unplanned ICU admission was also higher than that of patients without cancer [3]. In a systematic review, the ICU mortality rate of cancer patients was 38% but wide variations were round between the studies [4].…”

Section: Introductionmentioning

confidence: 96%

Mortality of cancer patients with septic shock: a nation-based cohort analysis in 77,888 patients

Bianchi,

Brousse,

Lakbar

et al. 2024

Preprint

View full text Add to dashboard Cite

Purpose: Septic shock and cancer occur routinely in intensive care unit patients. Our aim was to determine the 90-day mortality rate of patients with septic shock and solid cancer or hematological cancer. Methods: We performed a retrospective cohort study using data from the French national hospitalization database, including adult patients with septic shock from 2017 to 2018. Primary outcomes were the hospital mortality rate at 90 days in patients with solid cancer and hematological cancer. Secondary outcomes were the risk factors associated with mortality in our global cohort. Results: Septic shock was found in 77,888 patients, including 19,329 patients with solid cancer, 6,498 with hematological cancer and 52,061 noncancer patients. Patients with solid cancer (adjusted hazard ratio 1.55 [1.51-1.59]) and hematological cancer (1.59 [1.53-1.65]) had increased risk of 90-day mortality, as compared with noncancer patients. Risk factors for 90-days hospital mortality included hematological cancer and solid cancer. Conclusion: Our study showed that solid cancer and hematological cancer differed in terms of 90-days mortality in septic shock patients. Future investigations are required to assess the interplay between cancer and septic shock.

show abstract

“…2 Although earlier diagnosis, the introduction of new cancer treatments and intensive care advances have improved the prognosis of patients who require organ support during hospitalization, 3 in-hospital mortality continues to be higher than 40%. 4 For daily operation of hospital centers with a high volume of patients or with limited resources, it is necessary to have simple, low-cost tools or scales with clinical variables that can be obtained at the time of patient physical examination in order to allow patients at higher risk of death during hospitalization or at emergency services to be identified. Admitting cancer patients to intensive care units (ICU) is a complex decision, and in many hospital centers it is considered a low-priority measure in comparison with the needs of patients with non-oncological diseases.…”

Section: Introductionmentioning

confidence: 99%

Usefulness of the qSOFA score for predicting hospital mortality in cancer patients

Olvera-Alanis,

Óamendys-Silva,

Córdova-Sánchez

et al. 2024

GMM

View full text Add to dashboard Cite

Background:The quick Sequential Sepsis-related Organ Failure Assessment (qSOFA) is a score that has been proposed to quickly identify patients at higher risk of death. Objective: To describe the usefulness of the qSOFA score to predict in-hospital mortality in cancer patients. Material and methods: Cross-sectional study carried out between January 2021 and December 2022. Hospital mortality was the dependent variable. The area under the ROC curve (AUC) was calculated to determine the discriminative ability of qSOFA to predict in-hospital mortality. Results: A total of 587 cancer patients were included.

show abstract

A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

Cited by 8 publications

References 70 publications

Utilidad de la puntuación qSOFA para predecir mortalidad hospitalaria en pacientes con cáncer

Utilidad de la puntuación qSOFA para predecir mortalidad hospitalaria en pacientes con cáncer

Mortality of cancer patients with septic shock: a nation-based cohort analysis in 77,888 patients

Usefulness of the qSOFA score for predicting hospital mortality in cancer patients

Contact Info

Product

Resources

About