A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines

Abstract

Background. Aging is an inevitable stage of body development. At the same time, aging is a major cause of cancer, cardiovascular disease, and neurodegenerative diseases. Chinese herbal medicine is a natural substance that can effectively delay aging and is expected to be developed as antiaging drugs in the future. Aim of the review. This paper reviews the antiaging effects of 23 traditional Chinese herbal medicines or their active components. Materials and methods. We reviewed the literature published in the last five years on Chinese herbal medicines or their active ingredients and their antiaging role obtained through the following databases: PubMed, EMBASE, Scopus, and Web of Science. Results. A total of 2485 papers were found, and 212 papers were screened after removing the duplicates and reading the titles. Twenty-three studies met the requirements of this review and were included. Among these studies, 13 articles used Caenorhabditis elegans as the animal model, and 10 articles used other animal models or cell lines. Conclusion. Chinese herbal medicines or their active components play an antiaging role by regulating genes related to aging through a variety of signaling pathways. Chinese herbal medicines are expected to be developed as antiaging drugs or used in the medical cosmetology industry.

Sequentially fermentation of traditional Chinese medicine by Pichia kudriavzevii and bifidobacteria for Skin Care Function

“…The IIS pathway is the rst con rmed pathway to regulate aging [29] , Some of the antiaging effects of traditional Chinese medicine are involved in this pathway [30] , so hydroxyl radical scavenging of fermentation could re ect the antioxidant capacity of fermentation broth. Fig.…”

Sequentially fermentation of traditional Chinese medicine by Pichia kudriavzevii and bifidobacteria for Skin Care Function

“…The IIS pathway is the rst con rmed pathway to regulate aging (Kenyon C et al, 1993), Some of the antiaging effects of traditional Chinese medicinal are involved in this pathway (Wang L et al, 2021), so hydroxyl radical scavenging of fermentation could re ect the antioxidant capacity of fermentation broth. Fig.…”

The role ofCaenorhabditis elegansin the discovery of natural products for healthy aging

“…64) reviewed literature on C. elegans as model for frailty. Chattopadhyay and Thirumurugan 2018, 65 who reviewed 18 dietary and medicinal plants, and Wang et al 2021, 66 who focused on 23 plants from traditional Chinese medicine, both analyzed the longevity promoting effects of plant genera. Several reviews on the longevity promoting effect of natural compounds were also published.…”